Area of research
Molecular Biology · Cancer Research
Research interest
Research focused on RNA and Computational biology, with related work in Cell type, MFN2, Interoperability. Notable publications include 'The mRNA-Bound Proteome and Its Global Occupancy Profile on Protein-Coding Transcripts', 'A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain', and 'Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels'.
The two-step purification method ViREn identifies a single NSUN6-mediated 5-methylcytosine modification promoting dengue virus RNA genome turnover
The RMaP challenge of predicting RNA modifications by nanopore sequencing
Translon: a single term for translated regions
MoDorado: enhanced detection of tRNA modifications in nanopore sequencing by off-label use of modification callers
Genomic G quadruplexes regulate mRNA splicing
Sci-ModoM: a quantitative database of transcriptome-wide high-throughput RNA modification sites
APOBEC2 safeguards skeletal muscle cell fate through binding chromatin and regulating transcription of non-muscle genes during myoblast differentiation
SRSF2 safeguards efficient transcription of DNA damage and repair genes
Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision
Detection of queuosine and queuosine precursors in tRNAs by direct RNA sequencing
PEPseq quantifies transcriptome-wide changes in protein occupancy and reveals selective translational repression after translational stress
Rapid-CNS2: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study
Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional intercellular communication
Magnetique: an interactive web application to explore transcriptome signatures of heart failure
A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain
Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning
Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila
Increased susceptibility of human endothelial cells to infections by SARS-CoV-2 variants
Therapeutic inhibition of RBM20 improves diastolic function in a murine heart failure model and human engineered heart tissue
RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin
PATH-48. RAPID-CNS2: RAPID COMPREHENSIVE ADAPTIVE NANOPORE-SEQUENCING OF CNS TUMORS, A PROOF OF CONCEPT STUDY
Rapid-CNS <sup>2</sup> : Rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof of concept study
A MAFG-lncRNA axis links systemic nutrient abundance to hepatic glucose metabolism
Validation strategies for antibodies targeting modified ribonucleotides
Updated and enhanced pig cardiac transcriptome based on long-read RNA sequencing and proteomics
APOBEC2 is a Transcriptional Repressor required for proper Myoblast Differentiation
Deregulated Splicing Is a Major Mechanism of RNA-Induced Toxicity in Huntington's Disease
The lipid-droplet-associated protein ABHD5 protects the heart through proteolysis of HDAC4
A protein-RNA interaction atlas of the ribosome biogenesis factor AATF
RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin