Area of research
Neurology · Physiology
Research interest
Research focused on Chondrocyte and Osteoarthritis, with related work in Cell biology, Chaperone (clinical), Intracellular. Notable publications include 'Progranulin: A key player in autoimmune diseases', 'Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease', and 'Multifunctional molecule ERp57: From cancer to neurodegenerative diseases'.
Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis
Malate initiates a proton-sensing pathway essential for pH regulation of inflammation
Progranulin deficiency associates with postmenopausal osteoporosis via increasing ubiquitination of estrogen receptor α
14-3-3 epsilon is an intracellular component of TNFbib2 receptor complex and its activation protects against osteoarthritis
TNFR2/14-3-3ε signaling complex instructs macrophage plasticity in inflammation and autoimmunity
Digoxin targets low density lipoprotein receptor-related protein 4 and protects against osteoarthritis
Progranulin promotes bone fracture healing via TNFR pathways in mice with type 2 diabetes mellitus
Progranulin associates with Rab2 and is involved in autophagosome-lysosome fusion in Gaucher disease
Cytosolic Phospholipase A2 Is Required for Fexofenadine’s Therapeutic Effects against Inflammatory Bowel Disease in Mice
Repurposing FDA-approved drugs for SARS-CoV-2 through an ELISA-based screening for the inhibition of RBD/ACE2 interaction
Progranulin deficiency exacerbates spinal cord injury by promoting neuroinflammation and cell apoptosis in mice
Progranulin: A conductor of receptors orchestra, a chaperone of lysosomal enzymes and a therapeutic target for multiple diseases
Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis
Targeting tumor necrosis factor receptors in ankylosing spondylitis
Progranulin associates with hexosaminidase A and ameliorates GM2 ganglioside accumulation and lysosomal storage in Tay-Sachs disease
p204 Is Required for Canonical Lipopolysaccharide-induced TLR4 Signaling in Mice
Molecular regulations and therapeutic targets of Gaucher disease
Multifunctional molecule ERp57: From cancer to neurodegenerative diseases
Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models
Progranulin: A key player in autoimmune diseases
Progranulin Recruits HSP70 to β-Glucocerebrosidase and Is Therapeutic Against Gaucher Disease
Chondro-protective effects of low intensity pulsed ultrasound
The role of progranulin in arthritis