Area of research
Rheumatology · Environmental Chemistry
Research interest
Research focused on Osteoarthritis and Chondrocyte, with related work in Inflammation, Intracellular, Cell biology. Notable publications include 'Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis', '14-3-3 epsilon is an intracellular component of TNFbib2 receptor complex and its activation protects against osteoarthritis', and 'TNFR2/14-3-3ε signaling complex instructs macrophage plasticity in inflammation and autoimmunity'.
Nav1.7 as a chondrocyte regulator and therapeutic target for osteoarthritis
Progranulin deficiency associates with postmenopausal osteoporosis via increasing ubiquitination of estrogen receptor α
PGRN deficiency exacerbates, whereas a brain penetrant PGRN derivative protects, <i>GBA1</i> mutation-associated pathologies and diseases
14-3-3 epsilon is an intracellular component of TNFbib2 receptor complex and its activation protects against osteoarthritis
TNFR2/14-3-3ε signaling complex instructs macrophage plasticity in inflammation and autoimmunity
Roles and Mechanisms of Irisin in Attenuating Pathological Features of Osteoarthritis
Progranulin associates with Rab2 and is involved in autophagosome-lysosome fusion in Gaucher disease
Repurposing FDA-approved drugs for SARS-CoV-2 through an ELISA-based screening for the inhibition of RBD/ACE2 interaction
Fexofenadine inhibits TNF signaling through targeting to cytosolic phospholipase A2 and is therapeutic against inflammatory arthritis
p204 Is Required for Canonical Lipopolysaccharide-induced TLR4 Signaling in Mice
Progranulin derivative Atsttrin protects against early osteoarthritis in mouse and rat models
Foxo4‐ and Stat3‐dependent IL‐10 production by progranulin in regulatory T cells restrains inflammatory arthritis