Area of research
Cancer Research · Pulmonary and Respiratory Medicine
Research interest
Research interests include Cancer Genomics and Diagnostics, Lung Cancer Treatments and Mutations, Genetic factors in colorectal cancer, and Lung Cancer Research Studies.
Early identification of disease progression in ALK-rearranged lung cancer using circulating tumor DNA analysis
Earlier extracranial progression and shorter survival in ALK- rearranged lung cancer with positive liquid rebiopsies
Longitudinal therapy monitoring of ALK-positive lung cancer by combined copy number and targeted mutation profiling of cell-free DNA
Novel Liquid Biomarker Panels for A Very Early Response Capturing of NSCLC Therapies in Advanced Stages
Abstract A21: Longitudinal analysis of cell-free DNA for therapy monitoring of ALK-positive non-small cell lung cancer
Abstract 1571: Inter- and intra- tumorheterogeneity of the microenvironment in pulmonary adenocarcinoma
Detection of TP53 Mutations in Tissue or Liquid Rebiopsies at Progression Identifies ALK+ Lung Cancer Patients with Poor Survival
Defining molecular risk in ALK+ NSCLC
Circulating MicroRNAs as Potential Biomarkers for Lung Cancer
Serial liquid biopsies for detection of treatment failure and profiling of resistance mechanisms in <i>KLC1–ALK</i>-rearranged lung cancer
Multiple layers of intratumor heterogeneity: clues to clonal evolution of non-small cell lung cancer
TP53 status conversion defines an unfavourable patient subset with inferior overall survival in ALK+ lung adenocarcinoma
Global DNA methylation reflects spatial heterogeneity and molecular evolution of lung adenocarcinomas
Digital PCR After MALDI–Mass Spectrometry Imaging to Combine Proteomic Mapping and Identification of Activating Mutations in Pulmonary Adenocarcinoma
A field guide for cancer diagnostics using cell‐free DNA: From principles to practice and clinical applications
Spatial distribution of <i>EGFR</i> and <i>KRAS</i> mutation frequencies correlates with histological growth patterns of lung adenocarcinomas
Patient-specific molecular alterations are associated with metastatic clear cell renal cell cancer progressing under tyrosine kinase inhibitor therapy
Mutation analysis of circulating plasma DNA to determine response to EGFR tyrosine kinase inhibitor therapy of lung adenocarcinoma patients
Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients
Chancen und Grenzen der liquid biopsy für die Tumordiagnostik