Area of research
Pulmonary and Respiratory Medicine · Molecular Biology
Research interest
Research focused on Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Block (permutation group theory), with related work in Protein subunit, Cell biology, Immunotherapy. Notable publications include 'Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice', 'Design of multi-scale protein complexes by hierarchical building block fusion', and 'Reconfigurable asymmetric protein assemblies through implicit negative design'.
Design of high-affinity binders to immune modulating receptors for cancer immunotherapy
Design of soluble Notch agonists that drive T cell development and boost immunity
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies
Multivalent designed proteins neutralize SARS-CoV-2 variants of concern and confer protection against infection in mice
Reconfigurable asymmetric protein assemblies through implicit negative design
Design of multi-scale protein complexes by hierarchical building block fusion
Sex-related outcomes after fenestrated-branched endovascular aneurysm repair for thoracoabdominal aortic aneurysms in the U.S. Fenestrated and Branched Aortic Research Consortium