Area of research
Molecular Biology · Physiology
Research interest
Research focused on Endosome and Tachykinin receptor 1, with related work in G protein-coupled receptor, Cell biology, Irritable bowel syndrome. Notable publications include 'Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief', 'Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission', and 'Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome'.
Sustained endosomal release of a neurokinin-1 receptor antagonist from nanostars provides long-lasting relief of chronic pain
A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes
Application of a Sulfoxonium Ylide Electrophile to Generate Cathepsin X-Selective Activity-Based Probes
Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission