Area of research
Genetics · Surgery
Research interest
Research interests include Genetic Associations and Epidemiology, Lipoproteins and Cardiovascular Health, BRCA gene mutations in cancer, and Genomics and Rare Diseases.
Common-variant and rare-variant genetic architecture of heart failure across the allele-frequency spectrum
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations
Atrial Fibrillation and Clonal Hematopoiesis in <i>TET2</i> and <i>ASXL1</i>
Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization
Returning integrated genomic risk and clinical recommendations: The eMERGE study
Genome-wide association meta-analysis identifies risk loci for abdominal aortic aneurysm and highlights PCSK9 as a therapeutic target
A Multi-Ancestry Polygenic Risk Score for Coronary Heart Disease Based on an Ancestrally Diverse Genome-Wide Association Study and Population-Specific Optimization
Large-scale genome-wide association study of coronary artery disease in genetically diverse populations
Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations
Genome-wide polygenic score to predict chronic kidney disease across ancestries
Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure
Multiancestral polygenic risk score for pediatric asthma
Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases
Response to Li and Hopper
Genome-wide Modeling of Polygenic Risk Score in Colorectal Cancer Risk
Predictive Utility of Polygenic Risk Scores for Coronary Heart Disease in Three Major Racial and Ethnic Groups
Genetic Architecture of Abdominal Aortic Aneurysm in the Million Veteran Program
Minority-centric meta-analyses of blood lipid levels identify novel loci in the Population Architecture using Genomics and Epidemiology (PAGE) study
Polygenic Risk Score Identifies Patients at Increased Risk for Abdominal Aortic Aneurysm and May Benefit from Ultrasound Screening
Abstract 15209: <i>LPA</i> Variants Are Associated With Aortic Valve Stenosis, Heart Failure and Chronic Kidney Disease