Area of research
Oncology · Surgery
Research interest
Research focused on Organoid and Pancreatic cancer, with related work in Wnt signaling pathway, Biobank, LGR5. Notable publications include 'Organoid Models of Human and Mouse Ductal Pancreatic Cancer', 'A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity', and 'In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration'.
Patient-Derived Organoids Predict Treatment Response in Metastatic Colorectal Cancer
Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: drug screen optimization and correlation with patient response
Repeatability and reproducibility of the Forskolin-induced swelling (FIS) assay on intestinal organoids from people with Cystic Fibrosis
Centralized intestinal organoid generation is a feasible and safe approach for personalized medicine as demonstrated in the HIT-CF Europe Organoid Study
Modeling resistance of colorectal peritoneal metastases to immune checkpoint blockade in humanized mice
Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids
Patient-derived organoids as a predictive biomarker for treatment response in cancer patients
Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids
Quantifying single-cell ERK dynamics in colorectal cancer organoids reveals EGFR as an amplifier of oncogenic MAPK pathway signalling
CRISPR-Based Adenine Editors Correct Nonsense Mutations in a Cystic Fibrosis Organoid Biobank
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo
Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids
Long‐term expanding human airway organoids for disease modeling
Pancreatic cancer organoids recapitulate disease and allow personalized drug screening
A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity
Organoid Models of Human and Mouse Ductal Pancreatic Cancer
In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration
A Critical Role for the Wnt Effector Tcf4 in Adult Intestinal Homeostatic Self-Renewal