Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Wnt/β-catenin signaling in development and cancer, Cancer Genomics and Diagnostics, Cancer-related gene regulation, and CRISPR and Genetic Engineering.
Interleukin-3 coordinates glial-peripheral immune crosstalk to incite multiple sclerosis
Generation of precision preclinical cancer models using regulated in vivo base editing
Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants
An <i>In Vivo Kras</i> Allelic Series Reveals Distinct Phenotypes of Common Oncogenic Variants
GO: a functional reporter system to identify and enrich base editing activity
Lineage Reversion Drives WNT Independence in Intestinal Cancer
Distinct Colorectal Cancer–Associated APC Mutations Dictate Response to Tankyrase Inhibition
Optimized base editors enable efficient editing in cells, organoids and mice
An optimized toolkit for precision base editing