Area of research
Molecular Biology · Clinical Biochemistry
Research interest
Research interests include Sphingolipid Metabolism and Signaling, Advanced Glycation End Products research, Connexins and lens biology, and Chronic Kidney Disease and Diabetes.
Photocatalytic [4 + 2] Annulation Reaction of Amine and Olefin Mediated by Benzophenone for Tetrahydroquinoline Synthesis
Quercetin prevents the USP22-Snail1 signaling pathway to ameliorate diabetic tubulointerstitial fibrosis
Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer’s disease mouse model and proteomics analysis
USP22 aggravated diabetic renal tubulointerstitial fibrosis progression through deubiquitinating and stabilizing Snail1
Alkali-Driven Photoinduced N-Dealkylation of Aryl Tertiary Amines and Amides
USP9X prevents AGEs-induced upregulation of FN and TGF-β1 through activating Nrf2-ARE pathway in rat glomerular mesangial cells
The crosstalk between Sirt1 and Keap1/Nrf2/ARE anti-oxidative pathway forms a positive feedback loop to inhibit FN and TGF-β1 expressions in rat glomerular mesangial cells
Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating Sirt1 to resist AGEs-induced upregulation of fibronetin and transforming growth factor-β1 in rat glomerular messangial cells
Sirt1 resists advanced glycation end products-induced expressions of fibronectin and TGF-β1 by activating the Nrf2/ARE pathway in glomerular mesangial cells