Area of research
Molecular Biology · Physiology
Research interest
Research focused on Cancer research and Prodrug, with related work in Cancer stem cell, Sepsis, Inflammation. Notable publications include 'Enrichment-triggered prodrug activation demonstrated through mitochondria-targeted delivery of doxorubicin and carbon monoxide', 'Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy', and 'CD39 limits P2X7 receptor inflammatory signaling and attenuates sepsis-induced liver injury'.
Silencing of aryl hydrocarbon receptor repressor restrains Th17 cell immunity in autoimmune hepatitis
Free heme exacerbates colonic injury induced by anti-cancer therapy
Delivery of therapeutic carbon monoxide by gas-entrapping materials
Extracellular mitochondria drive CD8 T cell dysfunction in trauma by upregulating CD39
Heme oxygenase-1 mitigates liver injury and fibrosis via modulation of LNX1/Notch1 pathway in myeloid cells
Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer
Global deletion of NTPDase3 protects against diet-induced obesity by increasing basal energy metabolism
Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation
Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases
Altered aryl-hydrocarbon-receptor signalling affects regulatory and effector cell immunity in autoimmune hepatitis
Selective deletion of ENTPD1/CD39 in macrophages exacerbates biliary fibrosis in a mouse model of sclerosing cholangitis
Enrichment-triggered prodrug activation demonstrated through mitochondria-targeted delivery of doxorubicin and carbon monoxide
HIF-1α-induced xenobiotic transporters promote Th17 responses in Crohn's disease
CD39 limits P2X7 receptor inflammatory signaling and attenuates sepsis-induced liver injury
Cabozantinib Eradicates Advanced Murine Prostate Cancer by Activating Antitumor Innate Immunity
Distinct roles of ecto-nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) in liver regeneration and fibrosis
CD39 mediated regulation of Th17-cell effector function is impaired in juvenile autoimmune liver disease
A20 deficiency causes spontaneous neuroinflammation in mice
Sublethal heat treatment promotes epithelial-mesenchymal transition and enhances the malignant potential of hepatocellular carcinoma
Molecular Biomarkers of Vascular Dysfunction in Obstructive Sleep Apnea
Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy
B cell–intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice
A20 promotes liver regeneration by decreasing SOCS3 expression to enhance IL-6/STAT3 proliferative signals