Area of research
Hepatology · Immunology
Research interest
Research interests include Liver Diseases and Immunity, Adenosine and Purinergic Signaling, Immune Cell Function and Interaction, and Liver Disease Diagnosis and Treatment.
Multi-scaled transcriptomics of chronically inflamed nasal epithelium reveals immune-epithelial dynamics and tissue remodeling in nasal polyp formation
B and T cells: (Still) the dominant orchestrators in autoimmune hepatitis
Adenosine-mediated immune responses in inflammatory bowel disease
Silencing of aryl hydrocarbon receptor repressor restrains Th17 cell immunity in autoimmune hepatitis
Delivery of therapeutic carbon monoxide by gas-entrapping materials
Extracellular mitochondria drive CD8 T cell dysfunction in trauma by upregulating CD39
Regulatory T cells in autoimmune hepatitis: an updated overview
Human Leukocyte Antigen Profile Predicts Severity of Autoimmune Liver Disease in Children of European Ancestry
Aberrant hepatic trafficking of gut‐derived T cells is not specific to primary sclerosing cholangitis
Altered aryl-hydrocarbon-receptor signalling affects regulatory and effector cell immunity in autoimmune hepatitis
P2X7 receptor activation increases expression of caveolin-1 and formation of macrophage lipid rafts, thereby boosting CD39 activity
Eosinophils and Purinergic Signaling in Health and Disease
Selective deletion of ENTPD1/CD39 in macrophages exacerbates biliary fibrosis in a mouse model of sclerosing cholangitis
The metabolite BH4 controls T cell proliferation in autoimmunity and cancer
HIF-1α-induced xenobiotic transporters promote Th17 responses in Crohn's disease
The ectonucleotidases <scp>CD</scp>39 and <scp>CD</scp>73: Novel checkpoint inhibitor targets
CD39 limits P2X7 receptor inflammatory signaling and attenuates sepsis-induced liver injury
Regulatory T‐cell conditioning endows activated effector T cells with suppressor function in autoimmune hepatitis/autoimmune sclerosing cholangitis
CD39 mediated regulation of Th17-cell effector function is impaired in juvenile autoimmune liver disease
Phenotype and immune function of lymph node and peripheral blood CLL cells are linked to transendothelial migration
In autoimmune hepatitis type 1 or the autoimmune hepatitis–sclerosing cholangitis variant defective regulatory T‐cell responsiveness to IL‐2 results in low IL‐10 production and impaired suppression
Regulatory T cells: Mechanisms of suppression and impairment in autoimmune liver disease
Regulatory T-cells in autoimmune diseases: Challenges, controversies and—yet—unanswered questions
Alginate Microencapsulated Hepatocytes Optimised for Transplantation in Acute Liver Failure
Diagnostic criteria of autoimmune hepatitis
Characterization of Human CD39+ Th17 Cells with Suppressor Activity and Modulation in Inflammatory Bowel Disease
Dysfunctional CD39POS regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis
Biological functions of ecto-enzymes in regulating extracellular adenosine levels in neoplastic and inflammatory disease states
The interplay between regulatory and effector T cells in autoimmune hepatitis: Implications for innovative treatment strategies
The impaired immune regulation of autoimmune hepatitis is linked to a defective galectin-9/tim-3 pathway