Area of research
Hematology · Molecular Biology
Research interest
Research focused on Myeloid leukemia and Enhancer, with related work in Cancer research, Oncogene, CTCF. Notable publications include 'The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops', 'Molecular role of the PAX5‐ETV6 oncoprotein in promoting B‐cell acute lymphoblastic leukemia', and 'Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia'.
MECOM is a master repressor of myeloid differentiation through dose control of <i>CEBPA</i> in acute myeloid leukemia
Enhancer Hijacking Discovery in Acute Myeloid Leukemia by Pyjacker Identifies MNX1 Activation via Deletion 7q
Oncogene <i>EVI1</i> drives acute myeloid leukemia via a targetable interaction with CTBP2
Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including <i>MNX1</i> activation via deletion 7q
The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops
Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia
Derepression of retroelements in acute myeloid leukemia with 3q aberrations
Molecular role of the PAX5‐ETV6 oncoprotein in promoting B‐cell acute lymphoblastic leukemia