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Roger Mulet‐Lazaro

Erasmus MC Cancer Institute · NL
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Area of research
Molecular Biology · Hematology
Research interest
Research interests include Acute Myeloid Leukemia Research, Protein Degradation and Inhibitors, Epigenetics and DNA Methylation, and Cancer-related gene regulation.
h-index
11
citations
569
works
54
NIH funding
primary concept
Myeloid leukemia
email

Recent publications

MECOM is a master repressor of myeloid differentiation through dose control of <i>CEBPA</i> in acute myeloid leukemia
Blood 2025cited by 6position: middledoi
Enhancer Hijacking Discovery in Acute Myeloid Leukemia by Pyjacker Identifies MNX1 Activation via Deletion 7q
Blood Cancer Discovery 2025cited by 4position: middledoi
STAG2 mutations reshape the cohesin-structured spatial chromatin architecture to drive gene regulation in acute myeloid leukemia
Cell Reports 2024cited by 19position: middledoi
Oncogene <i>EVI1</i> drives acute myeloid leukemia via a targetable interaction with CTBP2
Science Advances 2024cited by 16position: middledoi
Epigenetic alterations affecting hematopoietic regulatory networks as drivers of mixed myeloid/lymphoid leukemia
Nature Communications 2024cited by 13position: firstdoi
Pyjacker identifies enhancer hijacking events in acute myeloid leukemia including <i>MNX1</i> activation via deletion 7q
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 2position: middledoi
Cellular and metabolic characteristics of pre-leukemic hematopoietic progenitors with GATA2 haploinsuficiency
Haematologica 2022cited by 6position: middledoi
<i>CEBPA</i> mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome
Blood 2021cited by 162position: middledoi
The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops
Nature Communications 2021cited by 76position: middledoi
Selective Requirement of MYB for Oncogenic Hyperactivation of a Translocated Enhancer in Leukemia
Cancer Discovery 2021cited by 40position: middledoi
Allele-specific expression of <i>GATA2</i> due to epigenetic dysregulation in <i>CEBPA</i> double-mutant AML
Blood 2021cited by 30position: firstdoi
Aberrant <scp>DNA</scp> methylation patterns in microsatellite stable human colorectal cancers define a new marker panel for the <scp>CpG</scp> island methylator phenotype
International Journal of Cancer 2021cited by 7position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Stanley van Herk · Utrecht University6 papers (2021–2025)Claudia Erpelinck-Verschueren · Utrecht University5 papers (2021–2025)Ruud Delwel · Utrecht University5 papers (2021–2024)Leonie Smeenk · Utrecht University4 papers (2021–2025)Claudia Gebhard · University of Regensburg4 papers (2021–2024)Marije Havermans · Utrecht University4 papers (2021–2025)Bas J. Wouters · Erasmus MC4 papers (2021–2025)Michael Rehli · University Hospital Regensburg4 papers (2021–2024)Eric M. Bindels · Erasmus MC4 papers (2021–2024)Dorien Pastoors · Utrecht University3 papers (2021–2025)Sophie Ottema · Utrecht University3 papers (2021–2025) · 3 papers (2024–2025)H. Berna Beverloo · Erasmus MC2 papers (2021–2025)Noèlia Díaz · Universidade de Santiago de Compostela2 papers (2024–2024)Johannes Zuber · Research Institute of Molecular Pathology2 papers (2021–2025)Tim Grob · Erasmus MC Cancer Institute2 papers (2021–2025)François G. Kavelaars · Erasmus MC Cancer Institute2 papers (2021–2024)Stefan Gröschel · University of Applied Sciences Worms2 papers (2021–2022)Andrea Arricibita Varea · Utrecht University2 papers (2021–2021)Juan M. Vaquerizas · European Bioinformatics Institute2 papers (2024–2024)
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