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Christopher B. Cooper

Johns Hopkins University · US
Area of research
Pulmonary and Respiratory Medicine · Physiology
Research interest
Research interests include Chronic Obstructive Pulmonary Disease (COPD) Research, Respiratory Support and Mechanisms, Asthma and respiratory diseases, and Cardiovascular and exercise physiology.
h-index
51
citations
10,739
works
389
NIH funding
primary concept
email

Recent publications

Deep Learning Estimation of Small Airway Disease from Inspiratory Chest Computed Tomography: Clinical Validation, Repeatability, and Associations with Adverse Clinical Outcomes in Chronic Obstructive Pulmonary Disease
American Journal of Respiratory and Critical Care Medicine 2025cited by 13position: middledoi
Association of Lung Quantitative CT Scan Textures With Systemic Inflammation and Mortality in COPD
CHEST Journal 2025cited by 7position: middledoi
Neutrophil-to-Lymphocyte Ratio as a Biomarker in Clinically Stable Chronic Obstructive Pulmonary Disease: SPIROMICS Cohort
Annals of the American Thoracic Society 2025cited by 5position: middledoi
Loss of Airway Phylogenetic Diversity Is Associated with Clinical and Pathobiological Markers of Disease Development in Chronic Obstructive Pulmonary Disease
American Journal of Respiratory and Critical Care Medicine 2024cited by 27position: middledoi
Vessel and Airway Characteristics in One-Year Computed Tomography–Defined Rapid Emphysema Progression: SPIROMICS
Annals of the American Thoracic Society 2024cited by 12position: middledoi
The Effect of Chronic Altitude Exposure on Chronic Obstructive Pulmonary Disease Outcomes in the SPIROMICS Cohort: An Observational Cohort Study
American Journal of Respiratory and Critical Care Medicine 2024cited by 10position: middledoi
Serum Immunoglobulin G Levels Are Associated with Risk for Exacerbations: An Analysis of SPIROMICS
American Journal of Respiratory and Critical Care Medicine 2024cited by 9position: middledoi
Association of Ground-Glass Opacities with Systemic Inflammation and Progression of Emphysema
American Journal of Respiratory and Critical Care Medicine 2024cited by 8position: middledoi
Design of the SPIROMICS Study of Early COPD Progression: SOURCE Study
Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation 2024cited by 6position: middledoi
Longitudinal Follow-Up of Participants With Tobacco Exposure and Preserved Spirometry
JAMA 2023cited by 41position: middledoi
Predicting severe chronic obstructive pulmonary disease exacerbations using quantitative CT: a retrospective model development and external validation study
The Lancet Digital Health 2023cited by 41position: middledoi
Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease
American Journal of Respiratory and Critical Care Medicine 2023cited by 33position: middledoi
Indoor Pollution and Lung Function Decline in Current and Former Smokers: SPIROMICS AIR
American Journal of Respiratory and Critical Care Medicine 2023cited by 24position: middledoi
A blood and bronchoalveolar lavage protein signature of rapid FEV1 decline in smoking-associated COPD
Scientific Reports 2023cited by 13position: middledoi
Bronchodilators in Tobacco-Exposed Persons with Symptoms and Preserved Lung Function
New England Journal of Medicine 2022cited by 96position: middledoi
Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease
American Journal of Respiratory and Critical Care Medicine 2022cited by 92position: middledoi
Reversible Airflow Obstruction Predicts Future Chronic Obstructive Pulmonary Disease Development in the SPIROMICS Cohort: An Observational Cohort Study
American Journal of Respiratory and Critical Care Medicine 2022cited by 45position: lastdoi
Design and rationale for the prospective treatment efficacy in IPF using genotype for NAC selection (PRECISIONS) clinical trial
BMC Pulmonary Medicine 2022cited by 40position: middledoi
Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort
Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation 2022cited by 34position: middledoi
Bronchodilator Responsiveness in Tobacco-Exposed People With or Without COPD
CHEST Journal 2022cited by 16position: middledoi
Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR
The Science of The Total Environment 2022cited by 14position: middledoi
Black carbon content in airway macrophages is associated with increased severe exacerbations and worse COPD morbidity in SPIROMICS
Respiratory Research 2022cited by 14position: middledoi
Association Among Chronic Obstructive Pulmonary Disease Severity, Exacerbation Risk, and Anxiety and Depression Symptoms in the SPIROMICS Cohort
Journal of the Academy of Consultation-Liaison Psychiatry 2022cited by 12position: middledoi
Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort
CHEST Journal 2022cited by 12position: middledoi
Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort
The Lancet Respiratory Medicine 2021cited by 197position: middledoi
Reconsidering the Utility of Race-Specific Lung Function Prediction Equations
American Journal of Respiratory and Critical Care Medicine 2021cited by 109position: middledoi
Objectively Measured Physical Activity in Patients with COPD: Recommendations from an International Task Force on Physical Activity
Chronic Obstructive Pulmonary Diseases Journal of the COPD Foundation 2021cited by 95position: middledoi
Lung microbiota associations with clinical features of COPD in the SPIROMICS cohort
npj Biofilms and Microbiomes 2021cited by 68position: middledoi
Identification of Sputum Biomarkers Predictive of Pulmonary Exacerbations in COPD
CHEST Journal 2021cited by 41position: middledoi
Genetic and non-genetic factors affecting the expression of COVID-19-relevant genes in the large airway epithelium
Genome Medicine 2021cited by 38position: middledoi

Grants

Collaborative Research: MFS-SPEED: AI-Driven Design of Architecturally Varied and Deconstructable Polymers for a Comprehensive Circular Plastics Economy
NSF2519576$804,3082025–2028PIRePORTER

Frequent collaborators

MeiLan K. Han · Seoul National University Hospital37 papers (2016–2025)Prescott G. Woodruff · Advanced ENT and Allergy37 papers (2016–2025)Nadia N. Hansel · Johns Hopkins Bayview Medical Center35 papers (2016–2025)R. Graham Barr · La Trobe University35 papers (2016–2025)Fernando J. Martínez · University of Massachusetts Chan Medical School34 papers (2016–2025)Robert Paine · University of Utah32 papers (2016–2025)Eric A. Hoffman · Roy J. Carver Charitable Trust26 papers (2016–2025)Richard E. Kanner · University of Utah26 papers (2016–2024)David Couper · University of North Carolina at Chapel Hill22 papers (2016–2024)Mark T. Dransfield · University of Minnesota Morris20 papers (2016–2024)Eugene R. Bleecker · University of Arizona20 papers (2016–2023)Jerry A. Krishnan · IIT Research Institute19 papers (2016–2025)Alejandro P. Comellas · University of Iowa19 papers (2016–2025)Jeffrey L. Curtis · VA Ann Arbor Healthcare System17 papers (2016–2025)Russell P. Bowler · University of Alabama at Birmingham16 papers (2017–2025)Stephen P. Peters · Johns Hopkins University16 papers (2018–2022)Igor Barjaktarević · University of California, Los Angeles15 papers (2018–2025)Wanda K. O’Neal · University of North Carolina at Chapel Hill14 papers (2016–2025)Victor E. Ortega · Wake Forest University11 papers (2018–2024)Donald P. Tashkin · Pulmonary and Critical Care Associates11 papers (2016–2024)