Area of research
Pulmonary and Respiratory Medicine · Rheumatology
Research interest
Dr. David Couper's faculty appointment is in the Collaborative Studies Coordinating Center (CSCC), a unit in the Department of Biostatistics. Dr. Couper has worked at the CSCC since 1998 and has been the coordinating center (CC) Principal Investigator for several clinical trials and observational studies. He is currently PI of the Coordinating Center for the Atherosclerosis Risk in Communities (ARIC) Study, the ARIC Neurocognitive Study (ARIC-NCS), and the Aging and Cognitive Health Evaluation in Elders (ACHIEVE) and the Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed with Crohn’s Disease (CAMEO clinical trials, as well as the PI of the Genomics and Informatics Center for the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS).
Correlations Within and Between Highly Multiplexed Proteomic Assays of Human Plasma
Hearing Intervention, Social Isolation, and Loneliness
Correlations Within and Between Highly Multiplexed Proteomic Assays of Human Plasma. Rooney MR, Chen J, Ballantyne CM, Hoogeveen RC, Boerwinkle E, Yu B, Walker KA, Schlosser P, Selvin E, Chatterjee N, Couper D, Grams ME, Coresh J. (2025). Clin Chem, 71 (6), 677–87.
— 2025cited by 0position: selected
Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men
Epidemiologic Features of Recovery From SARS-CoV-2 Infection
Loss of Airway Phylogenetic Diversity Is Associated with Clinical and Pathobiological Markers of Disease Development in Chronic Obstructive Pulmonary Disease
Vessel and Airway Characteristics in One-Year Computed Tomography–Defined Rapid Emphysema Progression: SPIROMICS
Serum Immunoglobulin G Levels Are Associated with Risk for Exacerbations: An Analysis of SPIROMICS
Association of Ground-Glass Opacities with Systemic Inflammation and Progression of Emphysema
Design of the SPIROMICS Study of Early COPD Progression: SOURCE Study
Phenotypes and Trajectories of Tobacco-Exposed Persons with Preserved Spirometry: Insights from Lung Volumes
Hearing intervention versus health education control to reduce cognitive decline in older adults with hearing loss in the USA (ACHIEVE): a multicentre, randomised controlled trial
Longitudinal Follow-Up of Participants With Tobacco Exposure and Preserved Spirometry
Factors Associated With Circulating Sex Hormones in Men
Pulmonary emphysema subtypes defined by unsupervised machine learning on CT scans
Repeatability of Pulmonary Quantitative Computed Tomography Measurements in Chronic Obstructive Pulmonary Disease
A blood and bronchoalveolar lavage protein signature of rapid FEV1 decline in smoking-associated COPD
Systemic Markers of Lung Function and Forced Expiratory Volume in 1 Second Decline across Diverse Cohorts
Dynamic and functional linkage between von Willebrand factor and ADAMTS-13 with aging: an Atherosclerosis Risk in Community study
Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease
Reversible Airflow Obstruction Predicts Future Chronic Obstructive Pulmonary Disease Development in the SPIROMICS Cohort: An Observational Cohort Study
Lung function impairment and risk of incident heart failure: the NHLBI Pooled Cohorts Study
Forced Expiratory Flow at 25%-75% Links COPD Physiology to Emphysema and Disease Severity in the SPIROMICS Cohort
Racial and Ethnic Differences in the Association Between Classical Cardiovascular Risk Factors and Common Carotid Intima‐Media Thickness: An Individual Participant Data Meta‐Analysis
Bronchodilator Responsiveness in Tobacco-Exposed People With or Without COPD
Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR
Association Among Chronic Obstructive Pulmonary Disease Severity, Exacerbation Risk, and Anxiety and Depression Symptoms in the SPIROMICS Cohort
Clinical Implications of Low Absolute Blood Eosinophil Count in the SPIROMICS COPD Cohort
The ARIC (Atherosclerosis Risk In Communities) Study
Association Between Preserved Ratio Impaired Spirometry and Clinical Outcomes in US Adults