Area of research
Virology · Infectious Diseases
Research interest
Research interests include HIV Research and Treatment, HIV/AIDS drug development and treatment, HIV/AIDS Research and Interventions, and vaccines and immunoinformatics approaches.
Contemporary HIV-1 envelope pseudovirus panels for detecting and assessing B cell lineages with broadly neutralizing antibody potential.
Recurrent mutations drive rapid HIV escape from two broadly neutralizing antibodies in vivo.
A polyvalent DNA prime with matched polyvalent protein/GLA-SE boost regimen elicited the most robust and broad IgG and IgG3 V1V2 binding antibody and CD4+ T cell responses among 13 HIV vaccine trials
Bayesian estimation of HIV acquisition dates for prevention trials
Characterization of Early Viral Populations in Infants Acquiring HIV Through Perinatal and Breastmilk Transmission: A Review of what is Currently Known and the Gaps that Need to be Addressed to Guide Passive HIV Immunization of Breastfeeding Infants
Differences in neutralization susceptibility between clade C HIV viruses from breastmilk versus contemporaneous circulating viruses from sexually acquired infections
Prevention efficacy of the broadly neutralizing antibody VRC01 depends on HIV-1 envelope sequence features.
Immune correlates analysis of the Imbokodo (HVTN 705/HPX2008) efficacy trial of a mosaic HIV-1 vaccine regimen evaluated in Southern African people assigned female sex at birth: a two-phase case-control study
Quantifying how single dose Ad26.COV2.S vaccine efficacy depends on Spike sequence features
Viral Envelope Evolution in Simian-HIV-Infected Neonate and Adult-Dam Pairs of Rhesus Macaques.
Neutralization profiles of HIV-1 viruses from the VRC01 Antibody Mediated Prevention (AMP) trials
Pharmacokinetic serum concentrations of VRC01 correlate with prevention of HIV-1 acquisition
Trivalent mosaic or consensus HIV immunogens prime humoral and broader cellular immune responses in adults
Effect of epitope variant co-delivery on the depth of CD8 T cell responses induced by HIV-1 conserved mosaic vaccines
Different evolutionary pathways of HIV-1 between fetus and mother perinatal transmission pairs indicate unique immune selection in fetuses
Tracking Changes in SARS-CoV-2 Spike: Evidence that D614G Increases Infectivity of the COVID-19 Virus
Emergence of SARS-CoV-2 through recombination and strong purifying selection
Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth
HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design
Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection
Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection
Phenotypic properties of transmitted founder HIV-1
Elucidation of Hepatitis C Virus Transmission and Early Diversification by Single Genome Sequencing