Area of research
Pathology and Forensic Medicine · Clinical Biochemistry
Research interest
Research interests include Systemic Sclerosis and Related Diseases, Metabolism and Genetic Disorders, Connective Tissue Growth Factor Research, and Pulmonary Hypertension Research and Treatments.
mRNA therapy corrects defective glutathione metabolism and restores ureagenesis in preclinical argininosuccinic aciduria
Biomarkers of haemodynamic severity of systemic sclerosis-associated pulmonary arterial hypertension by serum proteome analysis
mRNA therapy restores euglycemia and prevents liver tumors in murine model of glycogen storage disease
Systemic modified messenger RNA for replacement therapy in alpha 1-antitrypsin deficiency
Single Cell RNA Sequencing Identifies HSPG2 and APLNR as Markers of Endothelial Cell Injury in Systemic Sclerosis Skin
Skin Gene Expression Is Prognostic for the Trajectory of Skin Disease in Patients With Diffuse Cutaneous Systemic Sclerosis
Altered Dermal Fibroblasts in Systemic Sclerosis Display Podoplanin and CD90
A Proteome-Derived Longitudinal Pharmacodynamic Biomarker for Diffuse Systemic Sclerosis Skin
Fresolimumab treatment decreases biomarkers and improves clinical symptoms in systemic sclerosis patients
A Longitudinal Biomarker for the Extent of Skin Disease in Patients With Diffuse Cutaneous Systemic Sclerosis
Promotion of Inflammatory Arthritis by Interferon Regulatory Factor 5 in a Mouse Model
Chronic Toll-like receptor 4 stimulation in skin induces inflammation, macrophage activation, transforming growth factor beta signature gene expression, and fibrosis