Area of research
Cancer Research · Molecular Biology
Research interest
Research focused on Temozolomide and Glioma, with related work in PKM2, Histone, Gene knockdown. Notable publications include 'Polymer-locking fusogenic liposomes for glioblastoma-targeted siRNA delivery and CRISPR–Cas gene editing', 'Histone lactylation-derived LINC01127 promotes the self-renewal of glioblastoma stem cells via the cis-regulating the MAP4K4 to activate JNK pathway', and 'LncRNA‐Mediated TPI1 and PKM2 Promote Self‐Renewal and Chemoresistance in GBM'.
From pathology to therapy: A comprehensive review of ATRX mutation related molecular functions and disorders
Polymer-locking fusogenic liposomes for glioblastoma-targeted siRNA delivery and CRISPR–Cas gene editing
LncRNA‐Mediated TPI1 and PKM2 Promote Self‐Renewal and Chemoresistance in GBM
A novel nuclear RNA HSD52 scaffolding NONO/SFPQ complex modulates DNA damage repair to facilitate temozolomide resistance
Histone lactylation-derived LINC01127 promotes the self-renewal of glioblastoma stem cells via the cis-regulating the MAP4K4 to activate JNK pathway
HK3 stimulates immune cell infiltration to promote glioma deterioration
Using integrated analysis from multicentre studies to identify RNA methylation-related lncRNA risk stratification systems for glioma
Development and validation of a pyroptosis-related genes signature for risk stratification in gliomas
LncRNA-mediated TPI1 and PKM2 promote self-renewal and chemoresistance in GBM