Area of research
Genetics · Physiology
Research interest
Research interests include Glioma Diagnosis and Treatment, Telomeres, Telomerase, and Senescence, Cancer-related molecular mechanisms research, and CRISPR and Genetic Engineering.
Coordinated Role of Autophagy and ERAD in Maintaining Neuroendocrine Function by Preventing Prohormone Aggregation
Insights of immune cell heterogeneity, tumor-initiated subtype transformation, drug resistance, treatment and detecting technologies in glioma microenvironment
A novel nuclear RNA HSD52 scaffolding NONO/SFPQ complex modulates DNA damage repair to facilitate temozolomide resistance
CRISPR-assisted transcription activation by phase-separation proteins
Mechanism of SOX10 in ferroptosis of hippocampal neurons after intracerebral hemorrhage via the miR-29a-3p/ACSL4 axis
A Comprehensive Pan-Cancer Analysis of the Potential Biological Functions and Prognosis Values of RICTOR
HK3 stimulates immune cell infiltration to promote glioma deterioration
Using integrated analysis from multicentre studies to identify RNA methylation-related lncRNA risk stratification systems for glioma
LncRNA-mediated TPI1 and PKM2 promote self-renewal and chemoresistance in GBM
METTL3-mediated m6A modification stabilizes TERRA and maintains telomere stability
DNA Damage Repair in Brain Tumor Immunotherapy
Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice
Repurposing type I–F CRISPR–Cas system as a transcriptional activation tool in human cells
Live cell imaging and proteomic profiling of endogenous NEAT1 lncRNA by CRISPR/Cas9-mediated knock-in
Genome-wide profiling of adenine base editor specificity by EndoV-seq
DeepNitro: Prediction of Protein Nitration and Nitrosylation Sites by Deep Learning
The BUB3-BUB1 Complex Promotes Telomere DNA Replication
HuR regulates telomerase activity through TERC methylation
Correction of β-thalassemia mutant by base editor in human embryos
Effective gene editing by high-fidelity base editor 2 in mouse zygotes
Serum miR‐221 serves as a biomarker for Parkinson's disease
CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes
Human cells lacking coilin and Cajal bodies are proficient in telomerase assembly, trafficking and telomere maintenance
Disease mutant analysis identifies a novel function of DAXX in telomerase regulation and telomere maintenance
Business-Intelligence Queries with Order Dependencies in DB2
Whole-genome screening identifies proteins localized to distinct nuclear bodies
Inefficient exogenous loading of a tapasin‐dependent peptide onto <scp>HLA</scp>‐<scp>B</scp>*44:02 can be improved by acid treatment or fixation of target cells