Area of research
Molecular Biology · Genetics
Research interest
Research interests include CRISPR and Genetic Engineering, RNA and protein synthesis mechanisms, Chromatin Remodeling and Cancer, and Genomics and Chromatin Dynamics.
Comprehensive deletion landscape of CRISPR-Cas9 identifies minimal RNA-guided DNA-binding modules
Site-Specific Bioconjugation through Enzyme-Catalyzed Tyrosine–Cysteine Bond Formation
Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism
CasX enzymes comprise a distinct family of RNA-guided genome editors
Author Correction: CasX enzymes comprise a distinct family of RNA-guided genome editors
Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes
A thermostable Cas9 with increased lifetime in human plasma
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch
Rational design of a split-Cas9 enzyme complex
Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery
Exome sequencing to identify de novo mutations in sporadic ALS trios
Creating a neural specific chromatin landscape by npBAF and nBAF complexes