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Axel Imhof

MRC Laboratory of Molecular Biology · GB
Area of research
Molecular Biology
Research interest
Research interests include Genomics and Chromatin Dynamics, Epigenetics and DNA Methylation, RNA modifications and cancer, and RNA and protein synthesis mechanisms.
h-index
72
citations
21,032
works
335
NIH funding
primary concept
Biology
email

Recent publications

A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis
Immunity 2025cited by 22position: middledoi
Ezh2 Shapes T Cell Plasticity to Drive Atherosclerosis
Circulation 2025cited by 17position: middledoi
Multicenter Longitudinal Quality Assessment of MS-Based Proteomics in Plasma and Serum
Journal of Proteome Research 2025cited by 11position: middledoi
Multicenter evaluation of label-free quantification in human plasma on a high dynamic range benchmark set
Nature Communications 2025cited by 6position: middledoi
Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors
Nucleic Acids Research 2024cited by 19position: middledoi
Myeloid cells coordinately induce glioma cell-intrinsic and cell-extrinsic pathways for chemoresistance via GP130 signaling
Cell Reports Medicine 2024cited by 7position: middledoi
PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma
Nature Cancer 2023cited by 50position: middledoi
A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases
EBioMedicine 2023cited by 30position: middledoi
Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for γ‐secretase activity
EMBO Molecular Medicine 2022cited by 12position: middledoi
HMGN5, an RNA or Nucleosome binding protein - potentially switching between the substrates to regulate gene expression
bioRxiv (Cold Spring Harbor Laboratory) 2022cited by 4position: middledoi
Endotoxinemia Accelerates Atherosclerosis Through Electrostatic Charge–Mediated Monocyte Adhesion
Circulation 2020cited by 215position: middledoi
Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1
Nature Communications 2020cited by 139position: middledoi
Harmonization of quality metrics and power calculation in multi-omic studies
Nature Communications 2020cited by 98position: middledoi
PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex
Nature Communications 2018cited by 58position: middledoi
MIR sequences recruit zinc finger protein ZNF768 to expressed genes
Nucleic Acids Research 2018cited by 25position: middledoi
MacroH2A histone variants maintain nuclear organization and heterochromatin architecture
Journal of Cell Science 2017cited by 103position: middledoi
The novel component Kgd4 recruits the E3 subunit to the mitochondrial α-ketoglutarate dehydrogenase
Molecular Biology of the Cell 2014cited by 57position: middledoi
Heterogeneous Antibody-Based Activity Assay for Lysine Specific Demethylase 1 (LSD1) on a Histone Peptide Substrate
SLAS DISCOVERY 2014cited by 11position: middledoi
Stepwise Evolution of Essential Centromere Function in a <i>Drosophila</i> Neogene
Science 2013cited by 103position: middledoi
RNA-Interference Components Are Dispensable for Transcriptional Silencing of the Drosophila Bithorax-Complex
PLoS ONE 2013cited by 8position: middledoi
Df31 Protein and snoRNAs Maintain Accessible Higher-Order Structures of Chromatin
Molecular Cell 2012cited by 133position: middledoi
Myb-binding Protein 1a (Mybbp1a) Regulates Levels and Processing of Pre-ribosomal RNA
Journal of Biological Chemistry 2012cited by 41position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Gernot Längst · University of Regensburg4 papers (2012–2022)Ignasi Forné · Ludwig-Maximilians-Universität München2 papers (2018–2024) · 2 papers (2012–2018)Andreas Schmidt · North Carolina State University2 papers (2020–2020) · 2 papers (2012–2018)Stanley R. Riddell · Fred Hutch Cancer Center1 papers (2022–2022)Lothar Schermelleh · Ludwig-Maximilians-Universität München1 papers (2012–2012)Muhammad Ahmad Maqbool · University of Manchester1 papers (2018–2018)Claudia Gebhard · University of Regensburg1 papers (2020–2020)Christopher Nimsky · Goethe University Frankfurt1 papers (2022–2022)Matthias Mann · Novo Nordisk Foundation1 papers (2018–2018)Moritz Völker-Albert · ift Rosenheim1 papers (2018–2018)Gen Li · Tianjin University of Traditional Chinese Medicine1 papers (2024–2024)Christian Weber · Dana-Farber Cancer Institute1 papers (2025–2025)Yuting Wu · South China Agricultural University1 papers (2025–2025)Min Li · University of Birmingham1 papers (2024–2024)Kai Zhao · Qingdao University1 papers (2022–2022)Attila Németh · University of Regensburg1 papers (2012–2012)Ding Zhou · Harbin Medical University1 papers (2024–2024)Michael Kluge · University Hospital Leipzig1 papers (2018–2018)