Area of research
Molecular Biology · Structural Biology
Research interest
Research interests include RNA and protein synthesis mechanisms, Advanced Electron Microscopy Techniques and Applications, Bacteriophages and microbial interactions, and RNA modifications and cancer.
Sequential membrane- and protein-bound organelles compartmentalize genomes during phage infection
Multiscale structure of chromatin condensates explains phase separation and material properties
Erwinia phage Asesino is a nucleus-forming phage that lacks PhuZ
Integrative mapping reveals molecular features underlying the mechanism of nucleocytoplasmic transport
Cryo-electron tomography reveals the microtubule-bound form of inactive LRRK2
ExoSloNano: multimodal nanogold labels for identification of macromolecules in live cells and cryo-electron tomograms
The molecular architecture of the nuclear basket
An intron endonuclease facilitates interference competition between coinfecting viruses
Expanding insights from in situ cryo-EM
Cryo-Focused Ion Beam Milling of Cells
Bringing Structure to Cell Biology with Cryo-Electron Tomography
Identifying the core genome of the nucleus-forming bacteriophage family and characterization of Erwinia phage RAY
Identification of the bacteriophage nucleus protein interaction network
Molecular architecture of LRRK2 in association with cellular organelles
Investigating the early stages of infection of nucleus-forming jumbo phage
Comprehensive structure and functional adaptations of the yeast nuclear pore complex
The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems
Architecture and self-assembly of the jumbo bacteriophage nuclear shell
Subcellular organization of viral particles during maturation of nucleus-forming jumbo phage
A cytoskeletal vortex drives phage nucleus rotation during jumbo phage replication in E. coli
Revealing bacterial cell biology using cryo-electron tomography
The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems. Source data
The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems. Source data
The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually exclusive condensates with RNA and the membrane-associated M protein
HSP70 chaperones RNA-free TDP-43 into anisotropic intranuclear liquid spherical shells
Asymmetric localization of the cell division machinery during Bacillus subtilis sporulation
Generating Chromosome Geometries in a Minimal Cell From Cryo-Electron Tomograms and Chromosome Conformation Capture Maps
Structure of LRRK2 in Parkinson’s disease and model for microtubule interaction
The In Situ Structure of Parkinson’s Disease-Linked LRRK2
Preparing samples from whole cells using focused-ion-beam milling for cryo-electron tomography