Area of research
Molecular Biology · Immunology and Allergy
Research interest
Research focused on Cell biology and Extracellular matrix, with related work in Autophagy, Regeneration (biology), Stem cell. Notable publications include 'Guidelines for the use and interpretation of assays for monitoring autophagy', 'Extracellular matrix: A dynamic microenvironment for stem cell niche', and 'Cellular and molecular mechanisms of muscle atrophy'.
Collagen VI sustains cell stemness and chemotherapy resistance in glioblastoma
Ambra1 deficiency impairs mitophagy in skeletal muscle
Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis
EMILIN1 deficiency causes arterial tortuosity with osteopenia and connects impaired elastogenesis with defective collagen fibrillogenesis
Collagen VI ablation in zebrafish causes neuromuscular defects during developmental and adult stages
Autophagy in the mesh of collagen VI
The Polyphenol Pterostilbene Ameliorates the Myopathic Phenotype of Collagen VI Deficient Mice via Autophagy Induction
Fra-2–expressing macrophages promote lung fibrosis
Multimerin-2 maintains vascular stability and permeability
Collagen VI Deficiency Results in Structural Abnormalities in the Mouse Lung
Autosomal recessive Bethlem myopathy: A clinical, genetic and functional study
WITHDRAWN: Autosomal recessive Bethlem myopathy: A clinical, genetic and functional study
Loss of mitochondrial calcium uniporter rewires skeletal muscle metabolism and substrate preference
AMBRA1 Controls Regulatory T-Cell Differentiation and Homeostasis Upstream of the FOXO3-FOXP3 Axis
Collagen VI in healthy and diseased nervous system
The ablation of the matricellular protein EMILIN2 causes defective vascularization due to impaired EGFR-dependent IL-8 production affecting tumor growth
Gelatin–genipin‐based biomaterials for skeletal muscle tissue engineering
A novel murine model for arrhythmogenic cardiomyopathy points to a pathogenic role of Wnt signalling and miRNA dysregulation
Collagen VI is required for the structural and functional integrity of the neuromuscular junction
Extracellular Collagen VI Has Prosurvival and Autophagy Instructive Properties in Mouse Fibroblasts
Loss of EMILIN-1 Enhances Arteriolar Myogenic Tone Through TGF-β (Transforming Growth Factor-β)–Dependent Transactivation of EGFR (Epidermal Growth Factor Receptor) and Is Relevant for Hypertension in Mice and Humans
CMG2/ANTXR2 regulates extracellular collagen VI which accumulates in hyaline fibromatosis syndrome
Perturbations in cell signaling elicit early cardiac defects in mucopolysaccharidosis type II
Transcription Factor EB Controls Metabolic Flexibility during Exercise
Glycolytic-to-oxidative fiber-type switch and mTOR signaling activation are early-onset features of SBMA muscle modified by high-fat diet
Lack of collagen VI promotes neurodegeneration by impairing autophagy and inducing apoptosis during aging
Targeting of EMILIN-1 and EMILIN-2 to Fibrillin Microfibrils Facilitates their Incorporation into the Extracellular Matrix
Collagen VI–NG2 axis in human tendon fibroblasts under conditions mimicking injury response
Autophagy activation in COL6 myopathic patients by a low-protein-diet pilot trial
Heterogeneity of Collagen VI Microfibrils