Area of research
Molecular Biology · Physiology
Research interest
Research interests include Skeletal muscle, Biology, Endocrinology, Cell biology, Internal medicine, and Autophagy.
Mitochondrial calcium uptake declines during aging and is directly activated by oleuropein to boost energy metabolism and skeletal muscle performance
SEPN1-related myopathy depends on the oxidoreductase ERO1A and is druggable with the chemical chaperone TUDCA
The mitochondrial ATP-dependent potassium channel (mitoKATP) controls skeletal muscle structure and function
A combination of metformin and galantamine exhibits synergistic benefits in the treatment of sarcopenia
Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca2+ accumulation in spinobulbar muscular atrophy skeletal muscle
Signatures of muscle disuse in spaceflight and bed rest revealed by single muscle fiber proteomics
Activation of Akt–mTORC1 signalling reverts cancer‐dependent muscle wasting
Biofabricating murine and human myo‐substitutes for rapid volumetric muscle loss restoration
Muscle functional recovery is driven by extracellular vesicles combined with muscle extracellular matrix in a volumetric muscle loss murine model
Common Muscle Metabolic Signatures Highlight Arginine and Lysine Metabolism as Potential Therapeutic Targets to Combat Unhealthy Aging
CFTR corrector C17 is effective in muscular dystrophy, <i>in vivo</i> proof of concept in LGMDR3
PHD1 controls muscle mTORC1 in a hydroxylation-independent manner by stabilizing leucyl tRNA synthetase
Exercise‐dependent increases in protein synthesis are accompanied by chromatin modifications and increased MRTF‐SRF signalling
The Polyphenol Pterostilbene Ameliorates the Myopathic Phenotype of Collagen VI Deficient Mice via Autophagy Induction
Biofabricating murine and human myo-substitutes for rapid volumetric muscle loss restoration
DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass
Fibroblast growth factor 21 controls mitophagy and muscle mass
Inhibition of the Fission Machinery Mitigates OPA1 Impairment in Adult Skeletal Muscles
Skeletal muscle mTORC1 regulates neuromuscular junction stability
SELENON (SEPN1) protects skeletal muscle from saturated fatty acid-induced ER stress and insulin resistance
KBTBD13 is an actin-binding protein that modulates muscle kinetics
Ascorbic Acid Route to the Endoplasmic Reticulum: Function and Role in Disease
Transcriptional programming of lipid and amino acid metabolism by the skeletal muscle circadian clock
Decellularised skeletal muscles allow functional muscle regeneration by promoting host cell migration
Loss of mitochondrial calcium uniporter rewires skeletal muscle metabolism and substrate preference
A maladaptive ER stress response triggers dysfunction in highly active muscles of mice with SELENON loss
Skeletal Muscle-Specific Methyltransferase METTL21C Trimethylates p97 and Regulates Autophagy-Associated Protein Breakdown
Protective Role of Testicular Hormone INSL3 From Atrophy and Weakness in Skeletal Muscle
Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence
Beta-agonist stimulation ameliorates the phenotype of spinal and bulbar muscular atrophy mice and patient-derived myotubes