Area of research
Cellular and Molecular Neuroscience · Molecular Biology
Research interest
Research focused on Oxysterol and Cell biology, with related work in mTORC1, Sterol, Programmed cell death. Notable publications include 'Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex', 'The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response', and '7-Dehydrocholesterol is an endogenous suppressor of ferroptosis'.
Phosphorylation of CRYAB induces a condensatopathy to worsen post–myocardial infarction left ventricular remodeling
7-Dehydrocholesterol is an endogenous suppressor of ferroptosis
GPR161 structure uncovers the redundant role of sterol-regulated ciliary cAMP signaling in the Hedgehog pathway
Stereospecific Properties and Intracellular Transport of Novel Intrinsically Fluorescent Neurosteroids
Lysosomal GPCR-like protein LYCHOS signals cholesterol sufficiency to mTORC1
4β-Hydroxycholesterol is a prolipogenic factor that promotes SREBP1c expression and activity through the liver X receptor
Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis
25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner
Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders
Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex
Photoaffinity labeling with cholesterol analogues precisely maps a cholesterol-binding site in voltage-dependent anion channel-1
Different oxysterols have opposing actions at N-methyl-d-aspartate receptors
The Transcription Factor STAT-1 Couples Macrophage Synthesis of 25-Hydroxycholesterol to the Interferon Antiviral Response
Neurosteroids, stress and depression: Potential therapeutic opportunities