Area of research
Infectious Diseases · Virology
Research interest
Research interests include SARS-CoV-2 and COVID-19 Research, HIV Research and Treatment, COVID-19 Clinical Research Studies, and HIV/AIDS drug development and treatment.
Plasmodium yoelii infection induces lung injury by modulating type 2 conventional dendritic cells autophagy via the STAT3-IRF4 signaling
The construction of modular universal chimeric antigen receptor T (MU-CAR-T) cells by covalent linkage of allogeneic T cells and various antibody fragments
Development of a PCSK9-targeted nanoparticle vaccine to effectively decrease the hypercholesterolemia
The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis
Nanoparticles and Antiviral Vaccines
Glycopeptide Antibiotic Teicoplanin Inhibits Cell Entry of SARS-CoV-2 by Suppressing the Proteolytic Activity of Cathepsin L
CBX4 contributes to HIV‐1 latency by forming phase‐separated nuclear bodies and SUMOylating EZH2
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι
Infection of wild-type mice by SARS-CoV-2 B.1.351 variant indicates a possible novel cross-species transmission route
A bivalent nanoparticle vaccine exhibits potent cross-protection against the variants of SARS-CoV-2
Differential efficiencies to neutralize the novel mutants B.1.1.7 and 501Y.V2 by collected sera from convalescent COVID-19 patients and RBD nanoparticle-vaccinated rhesus macaques
Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) and Heptad Repeat (HR) of SARS-CoV-2 Elicit Robust Protective Immune Responses
TRIM28 promotes HIV-1 latency by SUMOylating CDK9 and inhibiting P-TEFb
Adenosine deaminase acting on RNA-1 (ADAR1) inhibits hepatitis B virus (HBV) replication by enhancing microRNA-122 processing
Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control
Long noncoding RNA NRON contributes to HIV-1 latency by specifically inducing tat protein degradation