Area of research
Physiology · Epidemiology
Research interest
Research interests include Adipose Tissue and Metabolism, Adipokines, Inflammation, and Metabolic Diseases, Obesity, Physical Activity, Diet, and Regulation of Appetite and Obesity.
Defining Hyperphagia for Improved Diagnosis and Management of MC4R Pathway–Associated Disease: A Roundtable Summary
Adipocyte FMO3-derived TMAO induces WAT dysfunction and metabolic disorders by promoting inflammasome activation in ageing
Structured care after a DSD diagnosis in childhood: a mixed methods evaluation of the Empower-DSD program
<scp>IMPROVE</scp> 2023: The 2nd International Meeting on Pathway‐Related Obesity: Vision & Evidence
Early-Onset of Obesity Model: Impact of Early-Onset Obesity on Comorbidity Risk and Life Expectancy
The Capability to Undergo ACSL4-Mediated Ferroptosis Is Acquired During Brown-like Adipogenesis and Affected by Hypoxia
Übergewicht und Adipositas im Kindes- und Jugendalter – ungenügende Versorgungslage aus Sicht der niedergelassenen Kinder- und Jugendärzte in Deutschland
Palmitic acid differently modulates extracellular vesicles and cellular fatty acid composition of SGBS adipocytes without impairing their insulin signaling
Obesity causes mitochondrial fragmentation and dysfunction in white adipocytes due to RalA activation
A spatiotemporal proteomic map of human adipogenesis
Adipocyte p53 coordinates the response to intermittent fasting by regulating adipose tissue immune cell landscape
Single nucleus RNA-sequencing integrated into risk variant colocalization discovers 17 cell-type-specific abdominal obesity genes for metabolic dysfunction-associated steatotic liver disease
Satisfaction with a new patient education program for children, adolescents, and young adults with differences of sex development (DSD) and their parents.
Child and adolescent obesity
Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease
Adipose cells and tissues soften with lipid accumulation while in diabetes adipose tissue stiffens
Understanding the Patient Experience of Hunger and Improved Quality of Life with Setmelanotide Treatment in POMC and LEPR Deficiencies
Quality of life outcomes in two phase 3 trials of setmelanotide in patients with obesity due to LEPR or POMC deficiency
Partial Hydrolyzed Protein as a Protein Source for Infant Feeding: Do or Don’t?
Development and evaluation of a patient education programme for children, adolescents, and young adults with differences of sex development (DSD) and their parents: study protocol of Empower-DSD
In situ hybridization to detect DNA amplification in extracellular vesicles
Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis
Macrophage-derived secretome is sufficient to confer olanzapine-mediated insulin resistance in human adipocytes
Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials
Factors affecting early-life intestinal microbiota development
FAM13A affects body fat distribution and adipocyte function
Once-Weekly Somapacitan vs Daily GH in Children With GH Deficiency: Results From a Randomized Phase 2 Trial
Predictive network modeling in human induced pluripotent stem cells identifies key driver genes for insulin responsiveness
Treatment of Hypothalamic Obesity with Dextroamphetamine: A Case Series
An individual participant data meta-analysis on metabolomics profiles for obesity and insulin resistance in European children