Area of research
Genetics · Neurology
Research interest
Research interests include Neuroinflammation and Neurodegeneration Mechanisms, Alzheimer's disease research and treatments, Neurogenesis and neuroplasticity mechanisms, and Genetics and Neurodevelopmental Disorders.
Astrocyte-intrinsic signaling of chitinase-like protein CHI3L1 drives inflammation and amplifies demyelination in neuromyelitis optica
Stage-specific CHI3L1/YKL-40 signaling controls generation of oligodendrocyte precursor cells through IL13Rα2-mediated ferroptosis
CHI3L1/YKL-40 signaling inhibits neurogenesis in models of Alzheimer’s disease
Unraveling the Roles of UBE3A in Neurodevelopment and Neurodegeneration
UBE3A stabilization of β-catenin preserves synaptic proteins essential for motor and cognitive functions in Angelman Syndrome
Bridging autophagy and endolysosomal dysfunction: Role of bridging integrator 1 in Alzheimer’s disease
Astrocyte-derived CHI3L1 signaling impairs neurogenesis and cognition in the demyelinated hippocampus
Nanometer-resolution tracking of single cargo reveals dynein motor mechanisms
Astrocyte-secreted C3 signaling impairs neuronal development and cognition in autoimmune diseases
Targeting TrkB–PSD-95 coupling to mitigate neurological disorders
Advancements in Immunity and Dementia Research: Highlights from the 2023 AAIC Advancements: Immunity Conference
Interlinked destinies: How ubiquitin-proteasome and autophagy systems underpin neurocognitive outcomes
CHI3L1 signaling impairs hippocampal neurogenesis and cognitive function in autoimmune-mediated neuroinflammation
Inhibition of complement C3 signaling ameliorates locomotor and visual dysfunction in autoimmune inflammatory diseases
Near-lifespan longitudinal tracking of brain microvascular morphology, topology, and flow in male mice
Modeling Cellular Crosstalk of Neuroinflammation Axis by Tri-cultures of iPSC-Derived Human Microglia, Astrocytes, and Neurons
Stem Cell-Based Neural Model Systems for Brain Disorders
Assays of Monitoring and Measuring Autophagic Flux for iPSC-Derived Human Neurons and Other Brain Cell Types
The Generation and Functional Characterization of Human Microglia-Like Cells Derived from iPS and Embryonic Stem Cells
Potential role of chitinase‐3‐like protein 1 (CHI3L1/YKL‐40) in neurodegeneration and Alzheimer's disease
Cross-platform validation of neurotransmitter release impairments in schizophrenia patient-derived <i>NRXN1</i> -mutant neurons
Generation of Human Neurons and Oligodendrocytes from Pluripotent Stem Cells for Modeling Neuron-Oligodendrocyte Interactions
Generation of Human Neurons and Oligodendrocytes from Pluripotent Stem Cells for Modeling Neuron-Oligodendrocyte Interactions
Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk
ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion
MicroRNA-196a promotes cervical cancer proliferation through the regulation of FOXO1 and p27Kip1
Dual Regulation of miRNA Biogenesis Generates Target Specificity in Neurotrophin-Induced Protein Synthesis