Area of research
Molecular Biology · Pulmonary and Respiratory Medicine
Research interest
Research focused on Pyroptosis and Neuroinflammation, with related work in Cell biology, Chitinase, Neurodegeneration. Notable publications include 'Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2', 'Epithelial Cell Mitochondrial Dysfunction and PINK1 Are Induced by Transforming Growth Factor- Beta1 in Pulmonary Fibrosis', and 'Chitinase 3-like-1 Promotes Streptococcus pneumoniae Killing and Augments Host Tolerance to Lung Antibacterial Responses'.
CHI3L1/YKL-40 signaling inhibits neurogenesis in models of Alzheimer’s disease
Chitinase 3–like-1 Inhibits Innate Antitumor and Tissue Remodeling Immune Responses by Regulating CD47-SIRPα– and CD24-Siglec10–Mediated Phagocytosis
CHI3L1 signaling impairs hippocampal neurogenesis and cognitive function in autoimmune-mediated neuroinflammation
Potential role of chitinase‐3‐like protein 1 (CHI3L1/YKL‐40) in neurodegeneration and Alzheimer's disease
Chi3l1 is a modulator of glioma stem cell states and a therapeutic vulnerability for glioblastoma
Mitochondrial Dysfunction as a Pathogenic Mediator of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis
Laminin α1 is a genetic modifier of TGF-β1–stimulated pulmonary fibrosis
IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses
Epithelial Cell Mitochondrial Dysfunction and PINK1 Are Induced by Transforming Growth Factor- Beta1 in Pulmonary Fibrosis
AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites
Chitotriosidase in the Pathogenesis of Inflammation, Interstitial Lung Diseases and COPD
Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2
Chitinase-Like Protein Brp-39/YKL-40 Modulates the Renal Response to Ischemic Injury and Predicts Delayed Allograft Function
Chitinase 3-like-1 Promotes Streptococcus pneumoniae Killing and Augments Host Tolerance to Lung Antibacterial Responses