Area of research
Molecular Biology · Oncology
Research interest
Research focused on Inflammation and Computational biology, with related work in DNA methylation, Enhancer, Differentially methylated regions. Notable publications include 'Molecular characterization and clinical relevance of m6A regulators across 33 cancer types', 'FACER: comprehensive molecular and functional characterization of epigenetic chromatin regulators', and 'Dynamic Organization of lncRNA and Circular RNA Regulators Collectively Controlled Cardiac Differentiation in Humans'.
Dissection of triple-negative breast cancer microenvironment and identification of potential therapeutic drugs using single-cell RNA sequencing analysis
Dissecting the cellular reprogramming and tumor microenvironment in left- and right-sided Colorectal Cancer by single cell RNA sequencing
CiTSA: a comprehensive platform provides experimentally supported signatures of cancer immunotherapy and analysis tools based on bulk and scRNA-seq data
Applicability of Anticancer Drugs for the Triple-Negative Breast Cancer Based on Homologous Recombination Repair Deficiency
Identifying individualized risk subpathways reveals pan-cancer molecular classification based on multi-omics data
Prognostic Features of the Tumor Immune Microenvironment in Glioma and Their Clinical Applications: Analysis of Multiple Cohorts
Vitexin inhibits APEX1 to counteract the flow-induced endothelial inflammation
Single-Cell Transcriptomic Analysis Reveals a Tumor-Reactive T Cell Signature Associated With Clinical Outcome and Immunotherapy Response In Melanoma
Nuclear UHRF1 is a gate-keeper of cellular AMPK activity and function
Combined homologous recombination repair deficiency and immune activation analysis for predicting intensified responses of anthracycline, cyclophosphamide and taxane chemotherapy in triple-negative breast cancer
Systematic analysis of enhancer regulatory circuit perturbation driven by copy number variations in malignant glioma
Dissecting immune cell stat regulation network reveals biomarkers to predict ICB therapy responders in melanoma
Hypermethylation of mitochondrial DNA in vascular smooth muscle cells impairs cell contractility
Laminar Flow Protects Vascular Endothelial Tight Junctions and Barrier Function via Maintaining the Expression of Long Non-coding RNA MALAT1
<scp>GABC</scp>: A comprehensive resource and Genome Atlas for Breast Cancer
Molecular characterization and clinical relevance of m6A regulators across 33 cancer types
Gain-of-Function Mutations: An Emerging Advantage for Cancer Biology
DNA methyltransferase 1 and Krüppel-like factor 4 axis regulates macrophage inflammation and atherosclerosis
A comprehensive overview of oncogenic pathways in human cancer
Identifying functions and prognostic biomarkers of network motifs marked by diverse chromatin states in human cell lines
Identifying subpathway signatures for individualized anticancer drug response by integrating multi-omics data
Identification of Cancer Dysfunctional Subpathways by Integrating DNA Methylation, Copy Number Variation, and Gene-Expression Data
FACER: comprehensive molecular and functional characterization of epigenetic chromatin regulators
Inference of patient‐specific subpathway activities reveals a functional signature associated with the prognosis of patients with breast cancer
Dynamic Organization of lncRNA and Circular RNA Regulators Collectively Controlled Cardiac Differentiation in Humans
DiseaseEnhancer: a resource of human disease-associated enhancer catalog
Global Prioritization of Disease Candidate Metabolites Based on a Multi-omics Composite Network
Genome-wide DNA methylome reveals the dysfunction of intronic microRNAs in major psychosis
Subpathway-GMir: identifying miRNA-mediated metabolic subpathways by integrating condition-specific genes, microRNAs, and pathway topologies
The DNA Methylome and Transcriptome of Different Brain Regions in Schizophrenia and Bipolar Disorder