Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Genetic Mapping and Diversity in Plants and Animals, Genetic and phenotypic traits in livestock, and Bioinformatics and Genomic Networks.
The China Brain Multi-omics Atlas Project (CBMAP)
VCF2PCACluster: a simple, fast and memory-efficient tool for principal component analysis of tens of millions of SNPs
Exome-wide association study identifies KDELR3 mutations in extreme myopia
A pangenome reference of 36 Chinese populations
Genome-wide association study using whole-genome sequencing identifies risk loci for Parkinson’s disease in Chinese population
Genome-wide genotype-serum proteome mapping provides insights into the cross-ancestry differences in cardiometabolic disease susceptibility
OTTERS: a powerful TWAS framework leveraging summary-level reference data
mBAT-combo: A more powerful test to detect gene-trait associations from GWAS data
Larger cerebral cortex is genetically correlated with greater frontal area and dorsal thickness
<i>Ggnbp2</i> regulates synaptic development and autophagy in motor neurons
Discovery of genomic loci of the human cerebral cortex using genetically informed brain atlases
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders
Circulating vitamin C concentration and risk of cancers: a Mendelian randomization study
Association and prediction of phenotypic traits from neuroimaging data using a multi-component mixed model excluding the target vertex
Genetic mechanisms of critical illness in COVID-19
Genomic and drug target evaluation of 90 cardiovascular proteins in 30,931 individuals
Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture
Analysis of DNA methylation associates the cystine–glutamate antiporter SLC7A11 with risk of Parkinson’s disease
The interplay between host genetics and the gut microbiome reveals common and distinct microbiome features for complex human diseases
Conditional GWAS analysis to identify disorder-specific SNPs for psychiatric disorders
<i>ATXN1</i> repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization
Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis
A unified framework for association and prediction from vertex‐wise grey‐matter structure
Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits
Prioritizing natural-selection signals from the deep-sequencing genomic data suggests multi-variant adaptation in Tibetan highlanders
Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation