Area of research
Molecular Biology · Genetics
Research interest
Research interests include Single-cell and spatial transcriptomics, Genetic Associations and Epidemiology, Genetic Mapping and Diversity in Plants and Animals, and Cancer Genomics and Diagnostics.
Optimized summary-statistic-based single-cell eQTL meta-analysis
Demuxafy: improvement in droplet assignment by integrating multiple single-cell demultiplexing and doublet detection methods
Molecular profiling of human substantia nigra identifies diverse neuron types associated with vulnerability in Parkinson’s disease
The generation of stable microvessels in ischemia is mediated by endothelial cell derived TRAIL
An integrated cell atlas of the lung in health and disease
Transitioning single-cell genomics into the clinic
OTTERS: a powerful TWAS framework leveraging summary-level reference data
Heritable defects in telomere and mitotic function selectively predispose to sarcomas
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution
Novel human pluripotent stem cell-derived hypothalamus organoids demonstrate cellular diversity
Single-cell eQTL mapping identifies cell type–specific genetic control of autoimmune disease
A single-cell and spatially resolved atlas of human breast cancers
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour
Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images
Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis
Chronic lung diseases are associated with gene expression programs favoring SARS-CoV-2 entry and severity
SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues
Stromal cell diversity associated with immune evasion in human triple‐negative breast cancer
The single-cell eQTLGen consortium
Itaconate controls the severity of pulmonary fibrosis
The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly
Author response: The single-cell eQTLGen consortium
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits
Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances
Comprehensive Multiple eQTL Detection and Its Application to GWAS Interpretation
Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes
Unraveling the polygenic architecture of complex traits using blood eQTL metaanalysis
Identifying gene targets for brain-related traits using transcriptomic and methylomic data from blood
Single-Cell Transcriptomic Analysis of Cardiac Differentiation from Human PSCs Reveals HOPX-Dependent Cardiomyocyte Maturation
Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma