Area of research
Molecular Biology · Computational Theory and Mathematics
Research interest
Research interests include Protein Structure and Dynamics, Computational Drug Discovery Methods, RNA and protein synthesis mechanisms, and Machine Learning in Bioinformatics.
Current and future directions in network biology
Critical assessment of variant prioritization methods for rare disease diagnosis within the rare genomes project
Assessing predictions on fitness effects of missense variants in HMBS in CAGI6
Impact of <scp>AlphaFold</scp> on structure prediction of protein complexes: The <scp>CASP15‐CAPRI</scp> experiment
Impact of AlphaFold on Structure Prediction of Protein Complexes: The CASP15-CAPRI Experiment
Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
Prediction of protein assemblies, the next frontier: The <scp>CASP14‐CAPRI</scp> experiment
Reduced miR-363-3p expression in non-small cell lung cancer is associated with gemcitabine resistance via targeting of CUL4A
DOAJ (DOAJ: Directory of Open Access Journals) 2021cited by 6position: middle
Blind prediction of homo‐ and hetero‐protein complexes: The CASP13‐CAPRI experiment
Assessment of blind predictions of the clinical significance of <i>BRCA1</i> and <i>BRCA2</i> variants
Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas
Homophilic CD44 Interactions Mediate Tumor Cell Aggregation and Polyclonal Metastasis in Patient-Derived Breast Cancer Models
The SERM/SERD bazedoxifene disrupts ESR1 helix 12 to overcome acquired hormone resistance in breast cancer cells
A mutation in the CACNA1C gene leads to early repolarization syndrome with incomplete penetrance: A Chinese family study
Estrogen receptor alpha somatic mutations Y537S and D538G confer breast cancer endocrine resistance by stabilizing the activating function-2 binding conformation
Identification of YbeY-Protein Interactions Involved in 16S rRNA Maturation and Stress Regulation in Escherichia coli
Overflow metabolism in Escherichia coli results from efficient proteome allocation
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer
Overcoming mutation-based resistance to antiandrogens with rational drug design
Blind prediction of interfacial water positions in CAPRI
Collaborative Research: Characterizing Spatial and Temporal Variations of Volcanic Rift Zones on Basaltic Shield Volcanoes: A Seismological Study at Kilauea and Mauna Loa, Hawaii
CAREER: Physics-Constrained Modeling of Molecular Texts, Graphs, and Images for Deciphering Protein-Protein Interactions
Collaborative Research: An Open Access Experiment to Seismically Image Galapagos Plume-Ridge Interaction
Gaining new insights into the magmatic and tectonic processes at Kilauea Volcano from analysis of data recorded by the 2018 RAPID OBS array
RAPID: COLLABORATIVE RESEARCH: OBS survey of Kilauea's submarine south flank following the May 4, 2018 M6.9 earthquake and Lower East Rift Zone eruption
CCF: EAGER: Dimension Reduction and Optimization Methods for Flexible Refinement of Protein Docking
CCF: EAGER: Dimension Reduction and Optimization Methods for Flexible Refinement of Protein Docking
Developing a comprehensive model of subduction and continental accretion at Cascadia
Collaborative Research: The Growth of the Tibetan Plateau - A Seismic Investigation of the Qilian Shan and Surrounding Tectonic Blocks
"Upgrading computational facilities for URI Seismology and Marine Geophysics"
"COLLABORATIVE RESEARCH: Compositional and thermal variations in the mantle transition zone from integrated seismological and petrological investigations"
Joint tomography using three-dimensional sensitivity of finite-frequency body and surface waves: Methods and application to the Iceland hotspot
Seismic Wave Propagation in the Oceanic Crust and Upper Mantle
Collaborative Research: Constructing Self-Consistent Seismological And Geodynamic Models Of The Iceland Mantle Plume
High-Resolution Mantle Discontinuity Structure Beneath Iceland and Hawaii
Investigation of Local Seismicity Recorded by the MELT Array
Investigation of Local Seismicity Recorded by the MELT Array
Models of the 3-D Stratigraphy of Glaciated Continental Shelves
Imaging the Pattern of Large-Scale Mantle Convection Beneath Mid-Ocean Ridges Through Upper Mantle Discontinuities