Chun Chen

Gut microbiota regulate Alzheimer’s disease pathologies and cognitive disorders via PUFA-associated neuroinflammation

Gut inflammation triggers C/EBPβ/δ‐secretase‐dependent gut‐to‐brain propagation of Aβ and Tau fibrils in Alzheimer’s disease

Targeting both BDNF/TrkB pathway and delta-secretase for treating Alzheimer's disease

Optimized TrkB Agonist Ameliorates Alzheimer’s Disease Pathologies and Improves Cognitive Functions via Inhibiting Delta-Secretase

C/EBPβ/AEP Signaling Regulates the Oxidative Stress in Malignant Cancers, Stimulating the Metastasis

Neurotrophic signaling deficiency exacerbates environmental risks for Alzheimer’s disease pathogenesis

Gut dysbiosis contributes to amyloid pathology, associated with C/EBPβ/AEP signaling activation in Alzheimer’s disease mouse model

Cerebrospinal fluid tau fragment correlates with tau PET: a candidate biomarker for tangle pathology

Transepithelial transport mechanisms of 7,8-dihydroxyflavone, a small molecular TrkB receptor agonist, in human intestinal Caco-2 cells

The prodrug of 7,8-dihydroxyflavone development and therapeutic efficacy for treating Alzheimer’s disease

WIN2017 at the University of California, Irvine

Stochastic Simulation Optimization: An Optimized Approach

Electroweak Symmetry Breaking, Flavor Mixing and the LHC

Collaborative Research: ITR: Very Efficient Network Simulation Methods for Auctioning and Collaborative Models of Air Traffic Management

SGER: Very Efficient Simulation for Engineering Design Problems

SGER: Very Efficient Simulation for Engineering Design Problems

Engineering Sciences for Modeling and Simulation-Based Life-Cycle Engineering: An Engineering Design Framework Integrating Robust Optimization and Structured Simulation

The Application of Homomorphic Deconvolution to Diagnostic Testing of Underground Power Cables