Area of research
Cell Biology · Molecular Biology
Research interest
Research interests include Hippo pathway signaling and YAP/TAZ, T-cell and B-cell Immunology, Genomics and Chromatin Dynamics, and Cancer-related gene regulation.
Ultrastable and versatile multimeric ensembles of FoxP3 on microsatellites
FoxP3 forms a head-to-head dimer in vivo and stabilizes its multimerization on adjacent microsatellites
FOXP3 recognizes microsatellites and bridges DNA through multimerization
Mutations from patients with IPEX ported to mice reveal different patterns of FoxP3 and Treg dysfunction
The transcription factor FoxP3 can fold into two dimerization states with divergent implications for regulatory T cell function and immune homeostasis