Area of research
Molecular Biology · Immunology
Research interest
Research interests include TGF-β signaling in diseases, interferon and immune responses, Ubiquitin and proteasome pathways, and Cancer-related gene regulation.
Revitalizing T cells: breakthroughs and challenges in overcoming T cell exhaustion.
Alpha-kinase 1 agonists derived from microbial metabolite inflame antitumour immunity.
Author Correction: TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.
Author Correction: Polymer–mRNA complexes for monocyte-trafficked, lymph node-targeted cancer vaccination
Polymer-mRNA complexes for monocyte-trafficked, lymph node-targeted cancer vaccination.
Mucosal immune response in biology, disease prevention and treatment
Mucosal immune response in biology, disease prevention and treatment.
Targeting FOXM1 condensates reduces breast tumour growth and metastasis
Targeting FOXM1 condensates reduces breast tumour growth and metastasis.
Emerging roles of lysine lactyltransferases and lactylation.
Ketogenic diet and cancer: multidimensional exploration and research
Targeting a key disulfide linkage to regulate RIG-I condensation and cytosolic RNA-sensing
Targeting a key disulfide linkage to regulate RIG-I condensation and cytosolic RNA-sensing.
EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy
EGFR: New Insights on Its Activation and Mutation in Tumor and Tumor Immunotherapy.
Lactylation in Cancer: Advances, Challenges, and Future Perspectives
Targeting biomolecular condensates to inhibit breast cancer.
RREB1: A Critical Transcription Factor, Integrates TGF‐β and RAS Signals to Drive Cancer Metastasis via Regulation of Enhancers
Lactylation in Cancer: Advances, Challenges, and Future Perspectives.
Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis
Alanyl-tRNA synthetase, AARS1, is a lactate sensor and lactyltransferase that lactylates p53 and contributes to tumorigenesis
TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence
TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.
TRIM25 predominately associates with anti-viral stress granules.
TGFβ family signaling in human stem cell self-renewal and differentiation
PARP1-DNA co-condensation: the driver of broken DNA repair.
UCHL5 is a putative prognostic marker in renal cell carcinoma: a study of UCHL family
Capturing Protein-Protein Interactions with Acidic Amino Acids Reactive Cross-Linkers.
Deubiquitylating Enzymes in Cancer and Immunity
MAVS deSUMOylation by SENP1 inhibits its aggregation and antagonizes IRF3 activation