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Dongyan Zhang

Nanfang Hospital ·
Area of research
Physiology · Epidemiology
Research interest
Research interests include Adipose Tissue and Metabolism, Liver Disease Diagnosis and Treatment, Lipid metabolism and biosynthesis, and Metabolism, Diabetes, and Cancer.
h-index
45
citations
11,559
works
70
NIH funding
primary concept
email

Recent publications

Lysophosphatidic acid triggers inflammation in the liver and white adipose tissue in rat models of 1-acyl-sn-glycerol-3-phosphate acyltransferase 2 deficiency and overnutrition
Proceedings of the National Academy of Sciences 2023cited by 22position: middledoi
Anti‐inflammatory effects of oestrogen mediate the sexual dimorphic response to lipid‐induced insulin resistance
The Journal of Physiology 2019cited by 68position: middledoi
Adipose glucocorticoid action influences whole‐body metabolism <i>via</i> modulation of hepatic insulin action
The FASEB Journal 2019cited by 21position: middledoi
Author Correction: Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo
Nature Medicine 2019cited by 2position: middledoi
Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo
Nature Medicine 2018cited by 302position: middledoi
Acetyl‐CoA Carboxylase Inhibition Reverses NAFLD and Hepatic Insulin Resistance but Promotes Hypertriglyceridemia in Rodents
Hepatology 2018cited by 251position: middledoi
Angptl8 antisense oligonucleotide improves adipose lipid metabolism and prevents diet-induced NAFLD and hepatic insulin resistance in rodents
Diabetologia 2018cited by 82position: middledoi
Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans
Cell Reports 2017cited by 157position: middledoi
Mechanisms by which a Very-Low-Calorie Diet Reverses Hyperglycemia in a Rat Model of Type 2 Diabetes
Cell Metabolism 2017cited by 90position: middledoi
Acetate mediates a microbiome–brain–β-cell axis to promote metabolic syndrome
Nature 2016cited by 1,292position: middledoi
Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance
Journal of Clinical Investigation 2016cited by 232position: middledoi
XBP1s Is an Anti-lipogenic Protein
Journal of Biological Chemistry 2016cited by 72position: middledoi
Imeglimin lowers glucose primarily by amplifying glucose-stimulated insulin secretion in high-fat-fed rodents
American Journal of Physiology-Endocrinology and Metabolism 2016cited by 71position: middledoi
Argininosuccinate synthetase regulates hepatic AMPK linking protein catabolism and ureagenesis to hepatic lipid metabolism
Proceedings of the National Academy of Sciences 2016cited by 62position: middledoi
Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes
Cell 2015cited by 701position: middledoi
Controlled-release mitochondrial protonophore reverses diabetes and steatohepatitis in rats
Science 2015cited by 280position: middledoi
FGF1 and FGF19 reverse diabetes by suppression of the hypothalamic–pituitary–adrenal axis
Nature Communications 2015cited by 129position: middledoi
Prevention of diet-induced hepatic steatosis and hepatic insulin resistance by second generation antisense oligonucleotides targeted to the longevity gene mIndy (Slc13a5)
Aging 2015cited by 39position: middledoi
Second‐generation antisense oligonucleotides against β‐catenin protect mice against diet‐induced hepatic steatosis and hepatic and peripheral insulin resistance
The FASEB Journal 2015cited by 23position: middledoi
Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans
Proceedings of the National Academy of Sciences 2014cited by 393position: middledoi
Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis
Nature Medicine 2014cited by 185position: middledoi
Tissue-Specific Differences in the Development of Insulin Resistance in a Mouse Model for Type 1 Diabetes
Diabetes 2014cited by 54position: middledoi
Muscle-specific activation of Ca2+/calmodulin-dependent protein kinase IV increases whole-body insulin action in mice
Diabetologia 2014cited by 24position: middledoi
Reversal of Hypertriglyceridemia, Fatty Liver Disease, and Insulin Resistance by a Liver-Targeted Mitochondrial Uncoupler
Cell Metabolism 2013cited by 228position: middledoi
Cellular Mechanisms by Which FGF21 Improves Insulin Sensitivity in Male Mice
Endocrinology 2013cited by 221position: middledoi
CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance
Proceedings of the National Academy of Sciences 2013cited by 158position: middledoi
Saturated and unsaturated fat induce hepatic insulin resistance independently of TLR-4 signaling and ceramide synthesis in vivo
Proceedings of the National Academy of Sciences 2013cited by 100position: middledoi
Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration
Nature Medicine 2012cited by 331position: middledoi
Role of patatin-like phospholipase domain-containing 3 on lipid-induced hepatic steatosis and insulin resistance in rats
Hepatology 2012cited by 87position: middledoi

Grants

PFI-TT: High-Yield Production and Processing of Boron Nitride Particles for Biomedical Applications
NSF2329746$549,3212023–2026PIRePORTER
I-Corps: High Brightness Fluorescence Reagents for Biomedical Applications
NSF1445106$50,0002014–2015PIRePORTER

Frequent collaborators

Gerald I. Shulman · Howard Hughes Medical Institute29 papers (2012–2023)Gary W. Cline · Yale University13 papers (2012–2019)Varman T. Samuel · Yale University13 papers (2012–2023)Rachel J. Perry · Yale University13 papers (2013–2019)João Paulo Camporez · Universidade de Ribeirão Preto11 papers (2013–2019)Kitt Falk Petersen · Yale University11 papers (2012–2023)Michael J. Jurczak · University of Pittsburgh11 papers (2013–2019)Daniel F. Vatner · Yale University8 papers (2012–2023) · 7 papers (2012–2018)Xian‐Man Zhang · Yale University6 papers (2012–2017)Mario Kahn · Yale University6 papers (2012–2023)Blas A. Guigni · CECOM Software Engineering Center5 papers (2013–2015)Abudukadier Abulizi · DecImmune Therapeutics (United States)4 papers (2015–2019)François R. Jornayvaz · University of Geneva4 papers (2013–2015)Anila K. Madiraju · Salk Institute for Biological Studies4 papers (2016–2019)Fitsum Guebre-Egziabher · Université Claude Bernard Lyon 13 papers (2012–2015)Richard G. Kibbey · Yale Cancer Center3 papers (2016–2016)Xian‐Man Zhang · Zhejiang Medicine (China)3 papers (2015–2019) · 3 papers (2012–2015) · 3 papers (2013–2013)