Area of research
Sensory Systems · Cancer Research
Research interest
Research focused on Hair cell and Wnt signaling pathway, with related work in Cell biology, Cochlea, Notch signaling pathway. Notable publications include 'Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway', 'Accelerating bioelectric functional development of neural stem cells by graphene coupling: Implications for neural interfacing with conductive materials', and 'Inhibition of Protein arginine methyltransferase 6 reduces reactive oxygen species production and attenuates aminoglycoside- and cisplatin-induced hair cell death'.
A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement
Inhibition of the HMGB1/RAGE axis protects against cisplatin-induced ototoxicity via suppression of inflammation and oxidative stress
Generation of innervated cochlear organoid recapitulates early development of auditory unit
Mitochondrial Homeostasis–Related lncRNAs are Potential Biomarkers for Predicting Prognosis and Immune Response in Lung Adenocarcinoma
Potential role of glucosamine-phosphate N-acetyltransferase 1 in the development of lung adenocarcinoma
Inhibition of Protein arginine methyltransferase 6 reduces reactive oxygen species production and attenuates aminoglycoside- and cisplatin-induced hair cell death
Age-related transcriptome changes in Sox2+ supporting cells in the mouse cochlea
Characterization of Lgr6+ Cells as an Enriched Population of Hair Cell Progenitors Compared to Lgr5+ Cells for Hair Cell Generation in the Neonatal Mouse Cochlea
Hedgehog Signaling Promotes the Proliferation and Subsequent Hair Cell Formation of Progenitor Cells in the Neonatal Mouse Cochlea
Characterization of the Transcriptomes of Lgr5+ Hair Cell Progenitors and Lgr5- Supporting Cells in the Mouse Cochlea
Insm1a Is Required for Zebrafish Posterior Lateral Line Development
Bone morphogenetic protein 4 promotes the survival and preserves the structure of flow-sorted Bhlhb5+ cochlear spiral ganglion neurons in vitro
Accelerating bioelectric functional development of neural stem cells by graphene coupling: Implications for neural interfacing with conductive materials
Co-regulation of the Notch and Wnt signaling pathways promotes supporting cell proliferation and hair cell regeneration in mouse utricles
Wnt activation followed by Notch inhibition promotes mitotic hair cell regeneration in the postnatal mouse cochlea
Bmi1 Regulates the Proliferation of Cochlear Supporting Cells Via the Canonical Wnt Signaling Pathway
Reduced TRMU expression increases the sensitivity of hair-cell-like HEI-OC-1 cells to neomycin damage in vitro
Characterization of Lgr5+ progenitor cell transcriptomes in the apical and basal turns of the mouse cochlea
The structural development of primary cultured hippocampal neurons on a graphene substrate
Bmi1 regulates auditory hair cell survival by maintaining redox balance
Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway
Ildr1b is essential for semicircular canal development, migration of the posterior lateral line primordium and hearing ability in zebrafish: implications for a role in the recessive hearing impairment DFNB42
Early postnatal virus inoculation into the scala media achieved extensive expression of exogenous green fluorescent protein in the inner ear and preserved auditory brainstem response thresholds