Area of research
Physiology · Cell Biology
Research interest
Research interests include Alzheimer's disease research and treatments, Cellular transport and secretion, Neuroinflammation and Neurodegeneration Mechanisms, and Bioinformatics and Genomic Networks.
Haploinsufficiency of ITSN1 is associated with a substantial increased risk of Parkinson’s disease
TBK1 interacts with tau and enhances neurodegeneration in tauopathy
Integrating multimodal data to support Alzheimer’s disease target prioritization
Large-scale proteomic analysis of Alzheimer’s disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation
Meta-Analysis of the Alzheimer’s Disease Human Brain Transcriptome and Functional Dissection in Mouse Models
Integrated analysis of the aging brain transcriptome and proteome in tauopathy
Retromer subunit, VPS29, regulates synaptic transmission and is required for endolysosomal function in the aging brain
Susceptibility to neurofibrillary tangles: role of the PTPRD locus and limited pleiotropy with other neuropathologies
Changes in the detergent‐insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression
Uncoupling neuronal death and dysfunction in Drosophila models of neurodegenerative disease
Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms
Genetic Susceptibility for Alzheimer Disease Neuritic Plaque Pathology
Common variants at 12q14 and 12q24 are associated with hippocampal volume
A coding variant in CR1 interacts with APOE-ɛ4 to influence cognitive decline