Area of research
Immunology · Virology
Research interest
Research focused on CD47 and Efferocytosis, with related work in Inflammation, Cell biology, Phagocytosis. Notable publications include 'CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis', 'A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer', and 'Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis'.
Pro-efferocytic nanotherapies reduce vascular inflammation without inducing anemia in a large animal model of atherosclerosis
Abstract 4147227: TET2-mediated Clonal Hematopoiesis Exacerbates Foam Cell Generation
Abstract 128: Safety And Efficacy Of Pro-efferocytic Nanoparticles To Treat Atherosclerosis In A Porcine Model
Safety and Efficacy of Proefferocytic Nanoparticles to Treat Atherosclerosis in a Porcine Model
The pleiotropic benefits of statins include the ability to reduce CD47 and amplify the effect of pro-efferocytic therapies in atherosclerosis
Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade
<sup>18</sup> F-Fluorodeoxyglucose-Positron Emission Tomography Imaging Detects Response to Therapeutic Intervention and Plaque Vulnerability in a Murine Model of Advanced Atherosclerotic Disease—Brief Report
A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer
CD47-blocking antibodies restore phagocytosis and prevent atherosclerosis
MicroRNA 139-5p coordinates APLNR-CXCR4 crosstalk during vascular maturation
<i>CDKN2B</i> Regulates <i>TGF</i> β Signaling and Smooth Muscle Cell Investment of Hypoxic Neovessels
Cyclin-dependent kinase inhibitor 2B regulates efferocytosis and atherosclerosis