Area of research
Molecular Biology · Clinical Biochemistry
Research interest
Research interests include Mitochondrial Function and Pathology, Metabolism and Genetic Disorders, ATP Synthase and ATPases Research, and RNA modifications and cancer.
Hypoxia ameliorates neurodegeneration and movement disorder in a mouse model of Parkinson’s disease
Mutations in mitochondrial ferredoxin FDX2 suppress frataxin deficiency
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
Exclusion of sulfide:quinone oxidoreductase from mitochondria causes Leigh-like disease in mice by impairing sulfide metabolism
Therapeutic hypoxia for mitochondrial disease via enhancement of hemoglobin affinity and inhibition of HIF-2α
On the dynamic and even reversible nature of Leigh syndrome: Lessons from human imaging and mouse models
MitoCarta3.0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations
TEFM regulates both transcription elongation and RNA processing in mitochondria
MitoTALEN reduces mutant mtDNA load and restores tRNAAla levels in a mouse model of heteroplasmic mtDNA mutation
Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals
POLRMT regulates the switch between replication primer formation and gene expression of mammalian mtDNA