Area of research
Immunology · Cancer Research
Research interest
Research focused on Chromatin and V(D)J recombination, with related work in CTCF, Cohesin, Chromosome conformation capture. Notable publications include 'Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment', 'Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria', and 'Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models'.
Phage display of environmental protein toxins and virulence factors reveals the prevalence, persistence, and genetics of antibody responses
Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models
Discovery proteomics in aging human skeletal muscle finds change in spliceosome, immunity, proteostasis and mitochondria
IL-1R signaling promotes STAT3 and NF-κB factor recruitment to distal cis-regulatory elements that regulate Il17a/f transcription
Extremely Long-Range Chromatin Loops Link Topological Domains to Facilitate a Diverse Antibody Repertoire
Constraints Contributed by Chromatin Looping Limit Recombination Targeting during Ig Class Switch Recombination
Architectural Protein Subclasses Shape 3D Organization of Genomes during Lineage Commitment
Localized DNA Demethylation at Recombination Intermediates during Immunoglobulin Heavy Chain Gene Assembly
Localized epigenetic changes induced by DH recombination restricts recombinase to DJH junctions