Area of research
Molecular Biology · Plant Science
Research interest
Research interests include Genomics and Chromatin Dynamics, Genomics and Phylogenetic Studies, RNA and protein synthesis mechanisms, and RNA Research and Splicing.
Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair
The Space Omics and Medical Atlas (SOMA) and international astronaut biobank
Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight
Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight
Enhancer-driven 3D chromatin domain folding modulates transcription in human mammary tumor cells
Genome and Clonal Hematopoiesis Stability Contrasts with Immune, cfDNA, mitochondrial, and telomere length changes to Short Duration Spaceflight
PrecisionFDA Truth Challenge V2: Calling variants from short and long reads in difficult-to-map regions
An automated 13.5 hour system for scalable diagnosis and acute management guidance for genetic diseases
ExpansionHunter Denovo: a computational method for locating known and novel repeat expansions in short-read sequencing data
Heterochromatin drives compartmentalization of inverted and conventional nuclei
ExpansionHunter: a sequence-graph-based tool to analyze variation in short tandem repeat regions
Measuring the reproducibility and quality of Hi-C data
Highly structured homolog pairing reflects functional organization of the Drosophila genome
The genome-wide multi-layered architecture of chromosome pairing in early Drosophila embryos
Publisher Correction: Heterochromatin drives compartmentalization of inverted and conventional nuclei
Integrative detection and analysis of structural variation in cancer genomes
Higher-Order Organization Principles of Pre-translational mRNPs
An Integrative Framework for Detecting Structural Variations in Cancer Genomes
Activation of proto-oncogenes by disruption of chromosome neighborhoods
Patterns of Growth and Decline in Lung Function in Persistent Childhood Asthma
Structural organization of the inactive X chromosome in the mouse
Invariant TAD Boundaries Constrain Cell-Type-Specific Looping Interactions between Promoters and Distal Elements around the CFTR Locus
Extremely Long-Range Chromatin Loops Link Topological Domains to Facilitate a Diverse Antibody Repertoire
RUNX1 contributes to higher-order chromatin organization and gene regulation in breast cancer cells
Genetics and Genomics of Longitudinal Lung Function Patterns in Individuals with Asthma
HiC-Pro: an optimized and flexible pipeline for Hi-C data processing
Condensin-driven remodelling of X chromosome topology during dosage compensation
Mapping Nucleosome Resolution Chromosome Folding in Yeast by Micro-C
Genome-wide Maps of Nuclear Lamina Interactions in Single Human Cells
High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila