Area of research
Molecular Biology · Cancer Research
Research interest
Research focused on Cancer research and Angiogenesis, with related work in Cell biology, Renal cell carcinoma, Gene silencing. Notable publications include 'iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding', 'A novel LncRNA HITT forms a regulatory loop with HIF-1α to modulate angiogenesis and tumor growth', and 'Upregulation of MiR-205 under hypoxia promotes epithelial–mesenchymal transition by targeting ASPP2'.
piR-27222 mediates PM2.5-induced lung cancer by resisting cell PANoptosis through the WTAP/m6A axis
iASPP is essential for HIF-1α stabilization to promote angiogenesis and glycolysis via attenuating VHL-mediated protein degradation
A long noncoding RNA sensitizes genotoxic treatment by attenuating ATM activation and homologous recombination repair in cancers
A novel LncRNA HITT forms a regulatory loop with HIF-1α to modulate angiogenesis and tumor growth
HDAC1-induced epigenetic silencing of ASPP2 promotes cell motility, tumour growth and drug resistance in renal cell carcinoma
iASPP Is an Antioxidative Factor and Drives Cancer Growth and Drug Resistance by Competing with Nrf2 for Keap1 Binding
Epigenetic silencing of ASPP1 confers 5‐FU resistance in clear cell renal cell carcinoma by preventing p53 activation
Upregulation of MiR-205 under hypoxia promotes epithelial–mesenchymal transition by targeting ASPP2