N.N. Alexandrov National Cancer Centre ·
Area of research
Genetics · Reproductive Medicine
Research interest
Research interests include BRCA gene mutations in cancer, Genetic Associations and Epidemiology, Estrogen and related hormone effects, and Ovarian cancer diagnosis and treatment.
Integrative multi-omics analyses to identify the genetic and functional mechanisms underlying ovarian cancer risk regions
Polygenic score distribution differences across European ancestry populations: implications for breast cancer risk prediction
Differences in polygenic score distributions in European ancestry populations: implications for breast cancer risk prediction
Aggregation tests identify new gene associations with breast cancer in populations with diverse ancestry
FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women
Spectrum and Frequency of Germline FANCM Protein-Truncating Variants in 44,803 European Female Breast Cancer Cases
Polygenic risk modeling for prediction of epithelial ovarian cancer risk
Rare germline copy number variants (CNVs) and breast cancer risk
Copy Number Variants Are Ovarian Cancer Risk Alleles at Known and Novel Risk Loci
Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk
Mendelian randomisation study of smoking exposure in relation to breast cancer risk
Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element
CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers
Rare Copy Number Variants (CNVs) and Breast Cancer Risk
Rare copy number variants (CNVs) and breast cancer risk
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes
Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk
Polygenic Risk Modelling for Prediction of Epithelial Ovarian Cancer Risk
Shared heritability and functional enrichment across six solid cancers
The FANCM:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer
Publisher Correction: Shared heritability and functional enrichment across six solid cancers
Fine-mapping of 150 breast cancer risk regions identifies 178 high confidence target genes
Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis
Variants in genes encoding small GTPases and association with epithelial ovarian cancer susceptibility
rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology
Shared heritability and functional enrichment across six solid cancers
Association analysis identifies 65 new breast cancer risk loci
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer