Area of research
Immunology · Rheumatology
Research interest
Research interests include T-cell and B-cell Immunology, Systemic Lupus Erythematosus Research, Immune Cell Function and Interaction, and Rheumatoid Arthritis Research and Therapies.
Specificity, length and luck drive gene rankings in association studies
Causal modelling of gene effects from regulators to programs to traits
FOXP3 expression depends on cell-type-specific cis-regulatory elements and transcription factor circuitry
Central control of dynamic gene circuits governs T cell rest and activation
Gene regulatory network inference from CRISPR perturbations in primary CD4+ T cells elucidates the genomic basis of immune disease
CRISPR screens decode cancer cell pathways that trigger γδ T cell detection
Base-editing mutagenesis maps alleles to tune human T cell functions
Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases