Area of research
Molecular Biology · Genetics
Research interest
Research interests include Glioma Diagnosis and Treatment, Neuroblastoma Research and Treatments, Epigenetics and DNA Methylation, and RNA modifications and cancer.
Proficiency Testing to Assess Technical Performance for CTC-Processing and Detection Methods in CANCER-ID
The landscape of genomic alterations across childhood cancers
Author Correction: The landscape of genomic alterations across childhood cancers
Dissecting telomere maintenance mechanisms in pediatric glioblastoma
Integrative Genome-Scale Analysis Identifies Epigenetic Mechanisms of Transcriptional Deregulation in Unfavorable Neuroblastomas
Telomere dysfunction and chromothripsis
Low-dose Actinomycin-D treatment re-establishes the tumoursuppressive function of P53 in <i>RELA</i>-positive ependymoma
Pediatric and Adult High-Grade Glioma Stem Cell Culture Models Are Permissive to Lytic Infection with Parvovirus H-1
TB-17A COMPREHENSIVE PAN-CANCER ANALYSIS OF CHILDHOOD MALIGNANCIES
Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers
The <scp>tRNA</scp> methyltransferase Dnmt2 is required for accurate polypeptide synthesis during haematopoiesis
Dynamic modulation of Dnmt2-dependent tRNA methylation by the micronutrient queuine
Chronic Inflammation Induces a Novel Epigenetic Program That Is Conserved in Intestinal Adenomas and in Colorectal Cancer
Cell culture models of pediatric high-grade glioma are susceptible to parvovirus-1 induced cytotoxicity
Genome Sequencing of SHH Medulloblastoma Predicts Genotype-Related Response to Smoothened Inhibition
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
Paediatric and adult glioblastoma: multiform (epi)genomic culprits emerge
p19-INK4d inhibits neuroblastoma cell growth, induces differentiation and is hypermethylated and downregulated in MYCN-amplified neuroblastomas
Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups
Guanine Nucleotide-Binding Protein α Subunit Hypofunction in Children with Short Stature and Disproportionate Shortening of the 4th and 5th Metacarpals
Abstract 3084: Epigenetic deregulation in H3.3-K27M mutant pediatric high-grade gliomas
Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
Oncolytic effects of parvovirus H‐1 in medulloblastoma are associated with repression of master regulators of early neurogenesis
Targeting H3.3 mutated pediatric high grade gliomas – A high throughput screening approach to identify novel therapeutic agents
Hotspot Mutations in H3F3A and IDH1 Define Distinct Epigenetic and Biological Subgroups of Glioblastoma
Dissecting the genomic complexity underlying medulloblastoma
Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations
Dnmt3a Protects Active Chromosome Domains against Cancer-Associated Hypomethylation
Abstract 1424: KCNJ2 comprises a marker of poor prognosis and a therapeutic target in non-WNT/non-SHH medulloblastoma