Area of research
Cancer Research · Oncology
Research interest
Research interests include Cancer Cells and Metastasis, Neurogenesis and neuroplasticity mechanisms, Cancer, Hypoxia, and Metabolism, and Nerve injury and regeneration.
Global profiling of protein lactylation in microglia in experimental high-altitude cerebral edema
Fatty acid oxidation fuels glioblastoma radioresistance with CD47-mediated immune evasion
BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia
A bioactive gypenoside (GP-14) alleviates neuroinflammation and blood brain barrier (BBB) disruption by inhibiting the NF-κB signaling pathway in a mouse high-altitude cerebral edema (HACE) model
Autophagy Is Essential for Neural Stem Cell Proliferation Promoted by Hypoxia
dsCellNet: A new computational tool to infer cell–cell communication networks in the developing and aging brain
Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells
Intermittent hypoxia treatment alleviates memory impairment in the 6-month-old APPswe/PS1dE9 mice and reduces amyloid beta accumulation and inflammation in the brain
Loss of Wip1 aggravates brain injury after ischaemia/reperfusion by overactivating microglia
Loss of O-GlcNAcylation on MeCP2 at Threonine 203 Leads to Neurodevelopmental Disorders
Dual blockade of CD47 and HER2 eliminates radioresistant breast cancer cells
Loss of O-GlcNAc transferase in neural stem cells impairs corticogenesis
Hypoxia Augments Cerebral Inflammation in a Dextran Sulfate Sodium-Induced Colitis Mouse Model
Neural progenitor cells-secreted exosomal miR-210 induced by hypoxia influences cell viability
Close Homolog of L1 Deficiency Exacerbated Intestinal Epithelial Barrier Function in Mouse Model of Dextran Sulfate Sodium-Induced Colitis
FG-4592 Improves Depressive-Like Behaviors through HIF-1-Mediated Neurogenesis and Synapse Plasticity in Rats
Opposite regulation of Wnt/β-catenin and Shh signaling pathways by Rack1 controls mammalian cerebellar development
Metformin administration prevents memory impairment induced by hypobaric hypoxia in rats
Hypoxia augments LPS-induced inflammation and triggers high altitude cerebral edema in mice
Neuroprotective effects of Ginkgo biloba extract and Ginkgolide B against oxygen–glucose deprivation/reoxygenation and glucose injury in a new in vitro multicellular network model
miR-210 Protects Renal Cell Against Hypoxia-induced Apoptosis by Targeting HIF-1 Alpha
Ketogenic diet improves the spatial memory impairment caused by exposure to hypobaric hypoxia through increased acetylation of histones in rats
WIP1 Phosphatase Plays a Critical Neuroprotective Role in Brain Injury Induced by High-Altitude Hypoxic Inflammation
WIP1 phosphatase is a critical regulator of adipogenesis through dephosphorylating PPARγ serine 112
Network-Based Approach to Identify Potential Targets and Drugs that Promote Neuroprotection and Neurorepair in Acute Ischemic Stroke
Methylene Blue Reduces Acute Cerebral Ischemic Injury via the Induction of Mitophagy
CDK4-mediated MnSOD activation and mitochondrial homeostasis in radioadaptive protection
Reduced Cerebral Oxygen Content in the DG and SVZ In Situ Promotes Neurogenesis in the Adult Rat Brain In Vivo
A method for establishing the high-altitude cerebral edema (HACE) model by acute hypobaric hypoxia in adult mice
Dissolved oxygen concentration in the medium during cell culture: Defects and improvements