Area of research
Immunology · Oncology
Research interest
Research focused on Cancer research and T-cell receptor, with related work in Cell biology, Cancer immunotherapy, KRAS. Notable publications include 'Distinct Signaling Cascades of TREM-1, TLR and NLR in Neutrophils and Monocytic Cells', 'HLA class I loss in metachronous metastases prevents continuous T cell recognition of mutated neoantigens in a human melanoma model', and 'Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy'.
Inhibition of p300/CREBBP catalytic activity drives context-dependent transcriptional activation in AML
Targeting mutated KRAS by HLA-A*02:01 restricted anti-KRAS TCR-mimic CAR and bispecific T cell engager
Menin-inhibition boosts CAR-T cell therapy against NPM1 mutated and KMT2A-rearranged acute myeloid leukemia
Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy
Identification of TRDV-TRAJ V domains in human and mouse T-cell receptor repertoires
Targeting the melanoma-associated antigen CSPG4 with HLA-C*07:01-restricted T-cell receptors
A bicistronic vector backbone for rapid seamless cloning and chimerization of αβT-cell receptor sequences
HLA class I loss in metachronous metastases prevents continuous T cell recognition of mutated neoantigens in a human melanoma model
Distinct Signaling Cascades of TREM-1, TLR and NLR in Neutrophils and Monocytic Cells